Hydrogels: properties and applications in biomedicine
TC Ho, CC Chang, HP Chan, TW Chung, CW Shu… - Molecules, 2022 - mdpi.com
Hydrogels are crosslinked polymer chains with three-dimensional (3D) network structures,
which can absorb relatively large amounts of fluid. Because of the high water content, soft …
which can absorb relatively large amounts of fluid. Because of the high water content, soft …
A detailed insight of the tumor targeting using nanocarrier drug delivery system
Human struggle against the deadly disease conditions is continued since ages. The
contribution of science and technology in fighting against these diseases cannot be ignored …
contribution of science and technology in fighting against these diseases cannot be ignored …
Cilostazol-loaded solid lipid nanoparticles: Bioavailability and safety evaluation in an animal model
Cilostazol (CLZ) is an antiplatelet agent with limited solubility (∼ 6 μg/ml at 25° C), poor
absorption and low oral bioavailability. In this study, solid lipid nanoparticles (SLNs) were …
absorption and low oral bioavailability. In this study, solid lipid nanoparticles (SLNs) were …
Advancements in rectal drug delivery systems: clinical trials, and patents perspective
The rectal route is an effective route for the local and systemic delivery of active
pharmaceutical ingredients. The environment of the rectum is relatively constant with low …
pharmaceutical ingredients. The environment of the rectum is relatively constant with low …
Macrophage targeting of nitazoxanide-loaded transethosomal gel in cutaneous leishmaniasis
Topical delivery is preferable over systemic delivery for cutaneous leishmaniasis, because
of its easy administration, reduced systemic adverse effects and low cost. Nitazoxanide …
of its easy administration, reduced systemic adverse effects and low cost. Nitazoxanide …
Statistically designed dexibuprofen loaded solid lipid nanoparticles for enhanced oral bioavailability
Abstract Dexibuprofen (DBPN), a non-steroidal anti-inflammatory drug (NSAID), exhibit its
action by inhibiting COX enzymes. It belongs to BCS class Ⅱ drugs, owing to its poor …
action by inhibiting COX enzymes. It belongs to BCS class Ⅱ drugs, owing to its poor …
Nano-drug delivery systems based on different targeting mechanisms in the targeted therapy of colorectal cancer
K Wang, R Shen, T Meng, F Hu, H Yuan - Molecules, 2022 - mdpi.com
Colorectal cancer (CRC) is a usual digestive tract malignancy and the third main cause of
cancer death around the world, with a high occurrence rate and mortality rate. Conventional …
cancer death around the world, with a high occurrence rate and mortality rate. Conventional …
Sodium alginate-based smart gastro-retentive drug delivery system of revaprazan loaded SLNs; Formulation and characterization
Revaprazan (REV), a novel reversible Proton Pump Inhibitor (PPI) used to treat peptic
ulcers, faces challenges in therapeutic efficacy due to its poor dissolution properties and a …
ulcers, faces challenges in therapeutic efficacy due to its poor dissolution properties and a …
Quality by design for sumatriptan loaded nano-ethosomal mucoadhesive gel for the therapeutic management of nitroglycerin induced migraine
Migraine is a progressive neurological condition often accompanied by nausea and
vomiting. Various drugs have recently been used in the treatment of migraine, including …
vomiting. Various drugs have recently been used in the treatment of migraine, including …
Statistical optimization of co-loaded rifampicin and pentamidine polymeric nanoparticles for the treatment of cutaneous leishmaniasis
Topical drug delivery against cutaneous leishmaniasis (CL) serves as an effective alternate
approach to improve efficacy and reduce systemic adverse effects. The purpose of this study …
approach to improve efficacy and reduce systemic adverse effects. The purpose of this study …