Human struggle against the deadly disease conditions is continued since ages. The contribution of science and technology in fighting against these diseases cannot be ignored …
Cilostazol (CLZ) is an antiplatelet agent with limited solubility (∼ 6 μg/ml at 25° C), poor absorption and low oral bioavailability. In this study, solid lipid nanoparticles (SLNs) were …
R Rathi, Sanshita, A Kumar, V Vishvakarma… - Pharmaceutics, 2022 - mdpi.com
The rectal route is an effective route for the local and systemic delivery of active pharmaceutical ingredients. The environment of the rectum is relatively constant with low …
H Khalid, S Batool, F Din, S Khan… - Royal society open …, 2022 - royalsocietypublishing.org
Topical delivery is preferable over systemic delivery for cutaneous leishmaniasis, because of its easy administration, reduced systemic adverse effects and low cost. Nitazoxanide …
B Imran, F ud Din, Z Ali, A Fatima, MW Khan… - Journal of Drug Delivery …, 2022 - Elsevier
Abstract Dexibuprofen (DBPN), a non-steroidal anti-inflammatory drug (NSAID), exhibit its action by inhibiting COX enzymes. It belongs to BCS class Ⅱ drugs, owing to its poor …
K Wang, R Shen, T Meng, F Hu, H Yuan - Molecules, 2022 - mdpi.com
Colorectal cancer (CRC) is a usual digestive tract malignancy and the third main cause of cancer death around the world, with a high occurrence rate and mortality rate. Conventional …
Revaprazan (REV), a novel reversible Proton Pump Inhibitor (PPI) used to treat peptic ulcers, faces challenges in therapeutic efficacy due to its poor dissolution properties and a …
U Shafique, F ud Din, S Sohail, S Batool… - International Journal of …, 2023 - Elsevier
Migraine is a progressive neurological condition often accompanied by nausea and vomiting. Various drugs have recently been used in the treatment of migraine, including …
MM Khan, SS Zaidi, FJ Siyal, SU Khan, G Ishrat… - Journal of Drug Delivery …, 2023 - Elsevier
Topical drug delivery against cutaneous leishmaniasis (CL) serves as an effective alternate approach to improve efficacy and reduce systemic adverse effects. The purpose of this study …