Chemotherapy-induced cognitive impairment and hippocampal neurogenesis: a review of physiological mechanisms and interventions

MJ Sekeres, M Bradley-Garcia… - International Journal of …, 2021 - mdpi.com
A wide range of cognitive deficits, including memory loss associated with hippocampal
dysfunction, have been widely reported in cancer survivors who received chemotherapy …

[HTML][HTML] Premature physiologic aging as a paradigm for understanding increased risk of adverse health across the lifespan of survivors of childhood cancer

KK Ness, JL Kirkland, MM Gramatges… - Journal of clinical …, 2018 - ncbi.nlm.nih.gov
The improvement in survival of childhood cancer observed across the past 50 years has
resulted in a growing acknowledgment that simply extending the lifespan of survivors is not …

Equitably improving outcomes for cancer survivors and supporting caregivers: a blueprint for care delivery, research, education, and policy

CM Alfano, CR Leach, TG Smith… - CA: a cancer journal …, 2019 - Wiley Online Library
Cancer care delivery is being shaped by growing numbers of cancer survivors coupled with
provider shortages, rising costs of primary treatment and follow‐up care, significant …

Measuring aging and identifying aging phenotypes in cancer survivors

JL Guida, TA Ahles, D Belsky, J Campisi… - JNCI: Journal of the …, 2019 - academic.oup.com
Observational data have shown that some cancer survivors develop chronic conditions like
frailty, sarcopenia, cardiac dysfunction, and mild cognitive impairment earlier and/or at a …

Frailty and aging in cancer survivors

KK Ness, MD Wogksch - Translational Research, 2020 - Elsevier
There are over 15 million survivors of cancer in the United States whose rates of frailty, an
aging phenotype, range from just under 10% to over 80%. Frailty impacts not only disease …

Sarcopenia and malignancies: epidemiology, clinical classification and implications

FM Zhang, HF Wu, HP Shi, Z Yu, CL Zhuang - Ageing Research Reviews, 2023 - Elsevier
Sarcopenia is a progressive systemic skeletal muscle disorder characterized by a
pathological decline in muscle strength, quantity, and quality, which frequently affects the …

Preclinical and clinical aspects of TNF-α and its receptors TNFR1 and TNFR2 in breast cancer

I Martínez-Reza, L Díaz, R García-Becerra - Journal of Biomedical Science, 2017 - Springer
Breast cancer is the most common malignancy in women and a public health problem
worldwide. Breast cancer is often accompanied by an inflammatory process characterized …

Inflammatory cytokine: an attractive target for cancer treatment

HM Lee, HJ Lee, JE Chang - Biomedicines, 2022 - mdpi.com
The relationship between inflammation and cancer has attracted attention for a long time.
The inflammatory tumor microenvironment consists of inflammatory cells, chemokines …

Depression and anxiety in colorectal cancer patients: Ties to pain, fatigue, and inflammation

ME Renna, MR Shrout, AA Madison… - Psycho …, 2022 - Wiley Online Library
Objective Colorectal cancer poses a significant threat to both psychological and physical
health. This study examined relationships between anxiety and depressive symptoms with …

Adipocytes in breast cancer, the thick and the thin

I Rybinska, R Agresti, A Trapani, E Tagliabue, T Triulzi - Cells, 2020 - mdpi.com
It is well established that breast cancer development and progression depend not only on
tumor-cell intrinsic factors but also on its microenvironment and on the host characteristics …