Risk factors of severe COVID-19: a review of host, viral and environmental factors
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …
asymptomatic infections to severe disease and death. Understanding the risk factors of …
The critically ill older patient with sepsis: a narrative review
M Ibarz, LEM Haas, A Ceccato, A Artigas - Annals of Intensive Care, 2024 - Springer
Sepsis is a significant public health concern, particularly affecting individuals above 70
years in developed countries. This is a crucial fact due to the increasing aging population …
years in developed countries. This is a crucial fact due to the increasing aging population …
Change in age distribution of COVID-19 deaths with the introduction of COVID-19 vaccination
Objectives Most countries initially deployed COVID-19 vaccines preferentially in elderly
populations. We aimed to evaluate whether population-level vaccine effectiveness is …
populations. We aimed to evaluate whether population-level vaccine effectiveness is …
Immunosenescence and altered vaccine efficiency in older subjects: A myth difficult to change
Organismal ageing is associated with many physiological changes, including differences in
the immune system of most animals. These differences are often considered to be a key …
the immune system of most animals. These differences are often considered to be a key …
Multimorbidity patterns in COVID-19 patients and their relationship with infection severity: MRisk-COVID study
M Lleal, C Corral-Vazquez, M Baré, R Comet… - Plos one, 2023 - journals.plos.org
Background Several chronic conditions have been identified as risk factors for severe
COVID-19 infection, yet the implications of multimorbidity need to be explored. The objective …
COVID-19 infection, yet the implications of multimorbidity need to be explored. The objective …
Approach to COVID-19 in older adults and indications for improving the outcomes
Background: COVID-19 continues to present challenges in the care of older adults with
frailty and/or comorbidities and very old patients, who can be hospitalized with severe …
frailty and/or comorbidities and very old patients, who can be hospitalized with severe …
Long-term effects of hospitalization for COVID-19 on frailty and quality of life in older adults≥ 80 years
Objectives: This study aimed to assess the effects of frailty and the perceived quality of life
(QOL) on the long-term survival (at least 1 year) of patients≥ 80 years hospitalized for …
(QOL) on the long-term survival (at least 1 year) of patients≥ 80 years hospitalized for …
Two years with COVID-19: the Electronic Frailty Index identifies high-risk patients in the Stockholm GeroCovid Study
Introduction: Frailty, a measure of biological aging, has been linked to worse COVID-19
outcomes. However, as the mortality differs across the COVID-19 waves, it is less clear …
outcomes. However, as the mortality differs across the COVID-19 waves, it is less clear …
Healthy aging, early screening, and interventions for frailty in the elderly
Y Deng, K Zhang, J Zhu, X Hu, R Liao - BioScience Trends, 2023 - jstage.jst.go.jp
With the intensification of population aging worldwide, the health problems of the elderly
have become a particular concern. Functional disability is a prominent problem in the aging …
have become a particular concern. Functional disability is a prominent problem in the aging …
The relationship between frailty, nutritional status, co-morbidity, CT-body composition and systemic inflammation in patients with COVID-19
J McGovern, Y Al-Azzawi, O Kemp, P Moffitt… - Journal of translational …, 2022 - Springer
Background Frailty, determined by the Canadian Study of Health and Aging-Clinical Frailty
Scale (CFS), is strongly associated with clinical outcomes including mortality in patients with …
Scale (CFS), is strongly associated with clinical outcomes including mortality in patients with …