Arthroplasty failure is a major complication of joint replacement surgery. It can be caused by
periprosthetic joint infection (PJI) or non-infectious etiologies, and often requires surgical …

Background: In the biotechnology and applied microbiology sectors, artificial intelligence
(AI) has been extensively used in disease diagnostics, drug research and development …

Background: Recently, multi-omic machine learning architectures have been proposed for
the early detection of cancer. However, for rare cancers and their associated small datasets …

The actin cytoskeleton plays essential roles in countless cell processes, from cell division to
migration to signaling. In cancer cells, cytoskeletal dynamics, cytoskeletal filament …

Over the past decade, genetic engineering has witnessed a revolution with the emergence
of a relatively new genetic editing tool based on RNA-guided nucleases: the CRISPR/Cas9 …

The advantages of genome selection (GS) in animal and plant breeding are self-evident.
Traditional parametric models have disadvantage in better fit the increasingly large …

In the age of high-throughput, single-cell biology, single-cell imaging has evolved not only in
terms of technological advancements but also in its translational applications. The …

Genomics has matured considerably over the last decades. Increasingly, genome-scale
genetic data are accompanied by other omic data: metabolomic, proteomic, epigenetic or …

Single-cell multi-omics is a rapidly evolving field, thanks to a fast technological improvement
and the growing accuracy of dedicated computational tools for data analysis. Its importance …

Aim: Computer-aided drug design (CADD) is a drug design technique for computing ligand–
receptor interactions and is involved in various stages of drug development. To better grasp …