Chemotherapy side-effects: not all DNA damage is equal

WMC van den Boogaard, DSJ Komninos, WP Vermeij - Cancers, 2022 - mdpi.com
Simple Summary The number of children and adults with cancer that are completely cured is
still increasing thanks to effective anti-cancer therapy, but they may be confronted with the …

Ageing as a software design flaw

JP de Magalhães - Genome Biology, 2023 - Springer
Ageing is inherent to all human beings, yet why we age remains a hotly contested topic.
Most mechanistic explanations of ageing posit that ageing is caused by the accumulation of …

Distinguishing between driver and passenger mechanisms of aging

JP de Magalhães - Nature Genetics, 2024 - nature.com
Understanding why we age is a long-standing question, and many mechanistic theories of
aging have been proposed. Owing to limitations in studying the aging process, including a …

Trends in droplet microfluidics: From droplet generation to biomedical applications

Z Chen, S Kheiri, EWK Young, E Kumacheva - Langmuir, 2022 - ACS Publications
Over the past decade, droplet microfluidics has attracted growing interest in biology,
medicine, and engineering. In this feature article, we review the advances in droplet …

Sirtuin 6: linking longevity with genome and epigenome stability

A Korotkov, A Seluanov, V Gorbunova - Trends in cell biology, 2021 - cell.com
Sirtuin 6 (SIRT6) has been in the spotlight of aging research because progeroid phenotypes
are associated with SIRT6 deficiency. SIRT6 has multiple molecular functions, including …

[HTML][HTML] Evidence of sex differences in cellular senescence

M Ng, LN Hazrati - Neurobiology of Aging, 2022 - Elsevier
Biological sex is a factor in many conditions, including aging, neurodegenerative disease,
cancer, and more. For each of these, men and women display distinct differences in disease …

[HTML][HTML] SIRT1 and SIRT6: The role in aging-related diseases

Y You, W Liang - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2023 - Elsevier
Aging is characterized by progressive functional deterioration with increased risk of
mortality. It is a complex biological process driven by a multitude of intertwined mechanisms …

Nutrition strategies promoting healthy aging: From improvement of cardiovascular and brain health to prevention of age-associated diseases

M Fekete, Z Szarvas, V Fazekas-Pongor, A Feher… - Nutrients, 2022 - mdpi.com
Background: An increasing number of studies suggest that diet plays an important role in
regulating aging processes and modulates the development of the most important age …

[PDF][PDF] Radha

M Kumar, S Prakash - Kumari, N, 2021 - refp.cohlife.org
Plant-derived phytochemicals have been touted as viable substitutes in a variety of
diseases. All over the world, dentists have turned to natural remedies for dental cure due to …

Genomic instability and epigenetic changes during aging

L López-Gil, A Pascual-Ahuir, M Proft - International Journal of Molecular …, 2023 - mdpi.com
Aging is considered the deterioration of physiological functions along with an increased
mortality rate. This scientific review focuses on the central importance of genomic instability …