[HTML][HTML] Extrachromosomal circular DNA: a neglected nucleic acid molecule in plants

H Peng, M Mirouze, E Bucher - Current Opinion in Plant Biology, 2022 - Elsevier
Throughout the years, most plant genomic studies were focused on nuclear chromosomes.
Extrachromosomal circular DNA (eccDNA) has largely been neglected for decades since its …

[HTML][HTML] Extrachromosomal circular DNA: Current status and future prospects

Y Zhao, L Yu, S Zhang, X Su, X Zhou - Elife, 2022 - elifesciences.org
Extrachromosomal circular DNA (eccDNA) is a double-stranded DNA molecule found in
various organisms, including humans. In the past few decades, the research on eccDNA has …

Extrachromosomal DNA in cancer

X Yan, P Mischel, H Chang - Nature Reviews Cancer, 2024 - nature.com
Extrachromosomal DNA (ecDNA) has recently been recognized as a major contributor to
cancer pathogenesis that is identified in most cancer types and is associated with poor …

The dynamic interplay between ribosomal DNA and transposable elements: a perspective from genomics and cytogenetics

S Garcia, A Kovarik, S Maiwald, L Mann… - Molecular Biology …, 2024 - academic.oup.com
Although both are salient features of genomes, at first glance ribosomal DNAs and
transposable elements are genetic elements with not much in common: whereas ribosomal …

CReSIL: accurate identification of extrachromosomal circular DNA from long-read sequences

V Wanchai, P Jenjaroenpun… - Briefings in …, 2022 - academic.oup.com
Extrachromosomal circular DNA (eccDNA) of chromosomal origin is found in many
eukaryotic species and cell types, including cancer, where eccDNAs with oncogenes drive …

[HTML][HTML] PlantLTRdb: An interactive database for 195 plant species LTR-retrotransposons

MM Mokhtar, AM Alsamman, A El Allali - Frontiers in Plant Science, 2023 - frontiersin.org
LTR-retrotransposons (LTR-RTs) are a large group of transposable elements that replicate
through an RNA intermediate and alter genome structure. The activities of LTR-RTs in plant …

[HTML][HTML] Pioneering insights of extrachromosomal DNA (ecDNA) generation, action and its implications for cancer therapy

Z Li, B Wang, H Liang, L Han - International Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Extrachromosomal DNA (ecDNA) is a cancer-specific circular DNA molecule that is derived
from chromosomes. In contrast with linear chromosomes, ecDNA exhibits a unique structure …

[HTML][HTML] Extrachromosomal DNA (ecDNA): Unveiling its role in cancer progression and implications for early detection

S Wu, T Tao, L Zhang, X Zhu, X Zhou - Heliyon, 2023 - cell.com
Extrachromosomal DNA (ecDNA) is a special class of circular DNA in eukaryotes, which is
independent of conventional chromosomes. These circular molecules play important roles in …

eccDB: a comprehensive repository for eccDNA-mediated chromatin contacts in multi-species

M Yang, B Qiu, GY He, JY Zhou, HJ Yu… - …, 2023 - academic.oup.com
We developed the eccDB database to integrate available resources for extrachromosomal
circular DNA (eccDNA) data. eccDB is a comprehensive repository for storing, browsing …

[HTML][HTML] Whole-genome sequencing of extrachromosomal circular DNA of cerebrospinal fluid of medulloblastoma

Y Zhu, Z Liu, Y Guo, S Li, Y Qu, L Dai, Y Chen… - Frontiers in …, 2022 - frontiersin.org
Background Medulloblastoma (MB) is a malignant tumor associated with a poor prognosis in
part due to a lack of effective detection methods. Extrachromosomal circular DNA (eccDNA) …