Y Zhao, L Yu, S Zhang, X Su, X Zhou - Elife, 2022 - elifesciences.org
Extrachromosomal circular DNA (eccDNA) is a double-stranded DNA molecule found in various organisms, including humans. In the past few decades, the research on eccDNA has …
X Yan, P Mischel, H Chang - Nature Reviews Cancer, 2024 - nature.com
Extrachromosomal DNA (ecDNA) has recently been recognized as a major contributor to cancer pathogenesis that is identified in most cancer types and is associated with poor …
Although both are salient features of genomes, at first glance ribosomal DNAs and transposable elements are genetic elements with not much in common: whereas ribosomal …
Extrachromosomal circular DNA (eccDNA) of chromosomal origin is found in many eukaryotic species and cell types, including cancer, where eccDNAs with oncogenes drive …
LTR-retrotransposons (LTR-RTs) are a large group of transposable elements that replicate through an RNA intermediate and alter genome structure. The activities of LTR-RTs in plant …
Z Li, B Wang, H Liang, L Han - International Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Extrachromosomal DNA (ecDNA) is a cancer-specific circular DNA molecule that is derived from chromosomes. In contrast with linear chromosomes, ecDNA exhibits a unique structure …
S Wu, T Tao, L Zhang, X Zhu, X Zhou - Heliyon, 2023 - cell.com
Extrachromosomal DNA (ecDNA) is a special class of circular DNA in eukaryotes, which is independent of conventional chromosomes. These circular molecules play important roles in …
M Yang, B Qiu, GY He, JY Zhou, HJ Yu… - …, 2023 - academic.oup.com
We developed the eccDB database to integrate available resources for extrachromosomal circular DNA (eccDNA) data. eccDB is a comprehensive repository for storing, browsing …
Y Zhu, Z Liu, Y Guo, S Li, Y Qu, L Dai, Y Chen… - Frontiers in …, 2022 - frontiersin.org
Background Medulloblastoma (MB) is a malignant tumor associated with a poor prognosis in part due to a lack of effective detection methods. Extrachromosomal circular DNA (eccDNA) …