Reprogramming of Treg cells in the inflammatory microenvironment during immunotherapy: a literature review

X Wu, Z Zhou, Q Cao, Y Chen, J Gong… - Frontiers in …, 2023 - frontiersin.org
Regulatory T cells (Treg), as members of CD4+ T cells, have garnered extensive attention in
the research of tumor progression. Treg cells have the function of inhibiting the immune …

T-cell exhaustion signatures characterize the immune landscape and predict HCC prognosis via integrating single-cell RNA-seq and bulk RNA-sequencing

H Chi, S Zhao, J Yang, X Gao, G Peng… - Frontiers in …, 2023 - frontiersin.org
Background Hepatocellular carcinoma (HCC), the third most prevalent cause of cancer-
related death, is a frequent primary liver cancer with a high rate of morbidity and mortality. T …

Circadian rhythm-related genes index: A predictor for HNSCC prognosis, immunotherapy efficacy, and chemosensitivity

H Chi, J Yang, G Peng, J Zhang, G Song, X Xie… - Frontiers in …, 2023 - frontiersin.org
Background Head and neck squamous cell carcinoma (HNSCC) is the most common head
and neck cancer and is highly aggressive and heterogeneous, leading to variable prognosis …

Deciphering the role of HPV-mediated metabolic regulation in shaping the tumor microenvironment and its implications for immunotherapy in HNSCC

X Gong, J Xiong, Y Gong, J Zhang, J Zhang… - Frontiers in …, 2023 - frontiersin.org
Head and neck squamous cell carcinoma (HNSCC), as a complex and variable malignancy,
poses a significant threat to human health. Since the intricate association between HPV and …

A fibroblast-associated signature predicts prognosis and immunotherapy in esophageal squamous cell cancer

Q Ren, P Zhang, X Zhang, Y Feng, L Li, H Lin… - Frontiers in …, 2023 - frontiersin.org
Background Current paradigms of anti-tumor therapies are not qualified to evacuate the
malignancy ascribing to cancer stroma's functions in accelerating tumor relapse and …

[HTML][HTML] Construction of a diagnostic model for hepatitis B-related hepatocellular carcinoma using machine learning and artificial neural networks and revealing the …

S Zhang, C Jiang, L Jiang, H Chen, J Huang… - Tumour Virus …, 2023 - Elsevier
HBV infection profoundly escalates hepatocellular carcinoma (HCC) susceptibility,
responsible for a majority of HCC cases. HBV-driven immune-mediated hepatocyte …

Mast cell marker gene signature: prognosis and immunotherapy response prediction in lung adenocarcinoma through integrated scRNA-seq and bulk RNA-seq

P Zhang, J Liu, S Pei, D Wu, J Xie, J Liu… - Frontiers in …, 2023 - frontiersin.org
Background Mast cells, comprising a crucial component of the tumor immune milieu,
modulate neoplastic progression by secreting an array of pro-and antitumorigenic factors …

An anoikis-related gene signature predicts prognosis and reveals immune infiltration in hepatocellular carcinoma

Y Chen, Q Lin, Y Xu, F Qian, C Lin, W Zhao… - Frontiers in …, 2023 - frontiersin.org
Background Hepatocellular carcinoma (HCC) is a global health burden with poor prognosis.
Anoikis, a novel programmed cell death, has a close interaction with metastasis and …

The role of different immunocompetent cell populations in the pathogenesis of head and neck cancer—regulatory mechanisms of pro-and anti-cancer activity and their …

K Starska-Kowarska - Cancers, 2023 - mdpi.com
Simple Summary According to the latest GLOBOCAN data, head and neck squamous cell
carcinoma (HNSCC) represents the sixth most prevalent human malignancy. Recent studies …

GADD45B regulates the carcinogenesis process of chronic atrophic gastritis and the metabolic pathways of gastric cancer

W Xu, T Jiang, K Shen, D Zhao, M Zhang… - Frontiers in …, 2023 - frontiersin.org
Background Gastric cancer continues to be a significant global healthcare challenge, and its
burden remains substantial. The development of gastric cancer (GC) is closely linked to …