[HTML][HTML] Human genetic factors associated with susceptibility to SARS-CoV-2 infection and COVID-19 disease severity

C Anastassopoulou, Z Gkizarioti, GP Patrinos… - Human genomics, 2020 - Springer
Background The emergence of the novel coronavirus in Wuhan, Hubei Province, China, in
December 2019 marked the synchronization of the world to a peculiar clock that is counting …

Genetic polymorphisms of ACE1, ACE2, and TMPRSS2 associated with COVID‐19 severity: A systematic review with meta‐analysis

W Saengsiwaritt, J Jittikoon… - Reviews in medical …, 2022 - Wiley Online Library
Abstract Novel coronavirus disease 2019 (COVID‐19) poses a global threat, due to its
fluctuating frequency and lethality. Published data revealed associations of COVID‐19 …

[HTML][HTML] Pan-sarbecovirus prophylaxis with human anti-ACE2 monoclonal antibodies

F Zhang, J Jenkins, RVH de Carvalho… - Nature …, 2023 - nature.com
Human monoclonal antibodies (mAbs) that target the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) spike protein have been isolated from convalescent …

[HTML][HTML] Pathogenesis and treatment of cytokine storm induced by infectious diseases

XD Tang, TT Ji, JR Dong, H Feng, FQ Chen… - International journal of …, 2021 - mdpi.com
Cytokine storm is a phenomenon characterized by strong elevated circulating cytokines that
most often occur after an overreactive immune system is activated by an acute systemic …

[HTML][HTML] TMPRSS2 polymorphism (rs12329760) and the severity of the COVID-19 in Iranian population

A Yaghoobi, JS Lord, JS Rezaiezadeh… - PLoS …, 2023 - journals.plos.org
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has been responsible for
the recent pandemic since early 2020. Due to the wide range of clinical symptoms of this …

[HTML][HTML] Pathways to ethnic inequalities in COVID-19 health outcomes in the United Kingdom: A systematic map

P Irizar, D Kapadia, S Amele, L Bécares, P Divall… - Social Science & …, 2023 - Elsevier
Background Marked ethnic inequalities in COVID-19 infection and its consequences have
been documented. The aim of this paper is to identify the range and nature of evidence on …

The polymorphism L412F in TLR3 inhibits autophagy and is a marker of severe COVID-19 in males

S Croci, MA Venneri, S Mantovani, C Fallerini… - Autophagy, 2022 - Taylor & Francis
The polymorphism L412F in TLR3 has been associated with several infectious diseases.
However, the mechanism underlying this association is still unexplored. Here, we show that …

[HTML][HTML] TogoVar: A comprehensive Japanese genetic variation database

N Mitsuhashi, L Toyo-Oka, T Katayama… - Human Genome …, 2022 - nature.com
Abstract TogoVar (https://togovar. org) is a database that integrates allele frequencies
derived from Japanese populations and provides annotations for variant interpretation. First …

Association of TLR3 functional variant (rs3775291) with COVID-19 susceptibility and death: a population-scale study

G Dhangadamajhi, R Rout - Human Cell, 2021 - Springer
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing the recent
pandemic of coronavirus disease-19 (COVID-19) has a long, positive-sense, non …

[HTML][HTML] The Pursuit of COVID-19 Biomarkers: Putting the Spotlight on ACE2 and TMPRSS2 Regulatory Sequences

A Barash, Y Machluf, I Ariel, Y Dekel - Frontiers in medicine, 2020 - frontiersin.org
Diverse populations worldwide are differentially affected by coronavirus disease 2019
(COVID-19). While socioeconomic background has been studied extensively, little is known …