Do men die young and sick, or do women live long and healthy? By trying to explain the
sexual dimorphism in life expectancy, both biological and environmental aspects are …

The significantly higher mortality rates seen in the elderly compared with young children
during the coronavirus disease 2019 (Covid‐19) pandemic is likely to be driven in part by an …

The common view is that T lymphocytes activate telomerase to delay senescence. Here we
show that some T cells (primarily naïve and central memory cells) elongated telomeres by …

Background Over the last two decades, progress in prevention and treatment of caries and
periodontal diseases has been translated to better oral health and improved tooth retention …

Inhibition of the mammalian target of rapamycin (mTOR) pathway extends life span in all
species studied to date, and in mice delays the onset of age-related diseases and …

Pathogen exposure elicits production of high‐affinity antibodies stimulated by T follicular
helper (Tfh) cells in the germinal center reaction. Tfh cells provide both costimulation and …

The most consequential challenge raised by coinfection is perhaps the inappropriate
generation of recombinant viruses through the exchange of genetic material among different …

As a hallmark of immunological aging, low-grade, chronic inflammation with accumulation of
effector memory T cells contributes to increased susceptibility to many aging-related …

Respiratory syncytial virus (RSV) is an exceptional mucosal pathogen. It specializes in
infection of the ciliated respiratory epithelium, causing disease of variable severity with little …

Aging affects all tissues and organs. Aging of the immune system results in the severe
disruption of its functions, leading to an increased susceptibility to infections, an increase in …