Aging is associated with changes to the immune system, collectively termed
immunosenescence and inflammageing. However, the relationships among age, frailty, and …

Aging has emerged at the forefront of scientific research due to the growing social and
economic costs associated with the growing aging global population. The defining features …

Immunological aging remodels the immune system at several levels. This has been
documented in particular for the T-cell receptor (TCR) αβ+ T-cell compartment, showing …

MicroRNAs play an important role in the regulation of T cell development, activation, and
differentiation. One of the most abundant microRNAs in lymphocytes is miR-181a, which …

The study examined sex-specificities in age-related changes in BALB/c mice IgG antibody
responses to immunisation with trivalent inactivated split-virus influenza bulk. Aging …

Elderly people are at high risk for influenza-related morbidity and mortality due to
progressive immunosenescence. While toll-like receptor (TLR) agonist containing adjuvants …

Background Aged individuals respond poorly to vaccination and have a higher risk of
contracting infections in comparison to younger individuals; whether age impacts on the …

The aging of the human population is posing serious challenges to research and to public
health authorities in order to prevent diseases that more frequently affect the elderly, a …

Careful management of immunosuppression is paramount to prevent acute rejection in
kidney transplantation. We studied a cohort of 139,875 kidney transplant recipients from the …

Circulating T follicular helper (cTfh) cells are known to be involved in numerous immune‐
mediated diseases, but their pathological role in psoriasis is less fully investigated. Herein …