Bone marrow: The central immune system

V Schirrmacher - Immuno, 2023 - mdpi.com
Bone marrow is known as the site of hematopoiesis. What is not being described in
textbooks of immunology is the fact that bone marrow is not only a generative, but also an …

Cannabidiol effect on long-term brain alterations in septic rats: Involvement of PPARγ activation

FF Gava, RJ De Carli, S Stork, LG Danielski… - Brain Research, 2024 - Elsevier
Sepsis is a life-threatening condition induced by a deregulated host response to infection.
Post-sepsis injury includes long-term cognitive impairment, whose neurobiological …

Identification of qualitative characteristics of immunosuppression in sepsis based on immune-related genes and immune infiltration features

N Zeng, Z Jian, J Xu, T Peng, G Hong, F Xiao - Heliyon, 2024 - cell.com
Objective Sepsis is linked to high morbidity and mortality rates. Consequently, early
diagnosis is crucial for proper treatment, reducing hospitalization, and mortality rates …

A hypoxia-and lactate metabolism-related gene signature to predict prognosis of sepsis: discovery and validation in independent cohorts

Y Peng, Q Wu, X Ding, L Wang, H Gong, C Feng… - European Journal of …, 2023 - Springer
Background High throughput gene expression profiling is a valuable tool in providing insight
into the molecular mechanism of human diseases. Hypoxia-and lactate metabolism-related …

[HTML][HTML] Uncovering hub genes in sepsis through bioinformatics analysis

Z Liu, E Qiu, B Yang, Y Zeng - Medicine, 2023 - journals.lww.com
In-depth studies on the mechanisms of pathogenesis of sepsis and diagnostic biomarkers in
the early stages may be the key to developing individualized and effective treatment …