Improved integration of single-cell transcriptome data demonstrates common and unique signatures of heart failure in mice and humans

MR Jurado, LS Tombor, M Arsalan, T Holubec… - …, 2024 - academic.oup.com
Background Cardiovascular research heavily relies on mouse (Mus musculus) models to
study disease mechanisms and to test novel biomarkers and medications. Yet, applying …

Somatic Cell Fusion in Host Defense and Adaptation

JL Platt, M Cascalho - Syncytia: Origin, Structure, and Functions, 2023 - Springer
Evidence of fusion of somatic cells has been noted in health and in disease for more than a
century. The most obvious but uncertain hallmark has been the presence of multiple nuclei …

Cardiovascular System, Its Functions and Disorders

JP Rabadia, VS Thite, BK Desai, RG Bera… - Cardioprotective Plants, 2024 - Springer
The cardiovascular structure comprises of the heart, arteries, veins, and capillaries. The
heart and vessels collectively and complexly deliver blood flow to all parts of the body. The …

Improved integration of single cell transcriptome data demonstrated on heart failure in mice and men

MR Jurado, LS Tombor, M Arsalan, T Holubec… - bioRxiv, 2023 - biorxiv.org
Biomedical research frequently uses murine models to study disease mechanisms.
However, the translation of these findings to human disease remains a significant challenge …

Cardiovascular System, Its Functions

JP Rabadia, VS Thite, BK Desai, RG Bera… - Cardioprotective … - books.google.com
The cardiovascular structure comprises of the heart, arteries, veins, and capillaries. The
heart and vessels collectively and complexly deliver blood flow to all parts of the body. The …