Early adversity and the development of explore–exploit tradeoffs

WE Frankenhuis, A Gopnik - Trends in Cognitive Sciences, 2023 - cell.com
Childhood adversity can have wide-ranging and long-lasting effects on later life. But what
are the mechanisms that are responsible for these effects? This article brings together the …

[HTML][HTML] Early social adversity, altered brain functional connectivity, and mental health

NE Holz, O Berhe, S Sacu, E Schwarz, J Tesarz… - Biological …, 2023 - Elsevier
Early adverse environmental exposures during brain development are widespread risk
factors for the onset of severe mental disorders and strong and consistent predictors of …

Early stress-induced impaired microglial pruning of excitatory synapses on immature CRH-expressing neurons provokes aberrant adult stress responses

JL Bolton, AK Short, S Othy, CL Kooiker, M Shao… - Cell reports, 2022 - cell.com
Several mental illnesses, characterized by aberrant stress reactivity, often arise after early-
life adversity (ELA). However, it is unclear how ELA affects stress-related brain circuit …

Neurobiology and systems biology of stress resilience

R Kalisch, SJ Russo, MB Müller - Physiological Reviews, 2024 - journals.physiology.org
Stress resilience is the phenomenon that some people maintain their mental health despite
exposure to adversity or show only temporary impairments followed by quick recovery …

[HTML][HTML] Early experience unpredictability in child development as a model for understanding the impact of the COVID-19 pandemic: A translational neuroscience …

S Liu, PA Fisher - Developmental Cognitive Neuroscience, 2022 - Elsevier
Extensive evidence links adverse experiences during childhood to a wide range of negative
consequences in biological, socioemotional, and cognitive development. Unpredictability is …

Early life exposure to unpredictable parental sensory signals shapes cognitive development across three species

EP Davis, K McCormack, H Arora, D Sharpe… - Frontiers in Behavioral …, 2022 - frontiersin.org
Exposure to early life adversity has long term consequences on cognitive function. Most
research has focused on understanding components of early life adversities that contribute …

Leveraging the science of stress to promote resilience and optimize mental health interventions during adolescence

DG Gee, LM Sisk, EM Cohodes, NV Bryce - nature communications, 2022 - nature.com
Adolescence is marked by heightened stress exposure and psychopathology, but also vast
potential for opportunity. We highlight how researchers can leverage both developmental …

[HTML][HTML] Neighborhood poverty during childhood prospectively predicts adolescent functional brain network architecture

C Michael, S Tillem, CS Sripada, SA Burt… - Developmental …, 2023 - Elsevier
Family poverty has been associated with altered brain structure, function, and connectivity in
youth. However, few studies have examined how disadvantage within the broader …

[HTML][HTML] Early childhood household instability, adolescent structural neural network architecture, and young adulthood depression: A 21-year longitudinal study

FA Hardi, LG Goetschius, S Tillem, V McLoyd… - Developmental …, 2023 - Elsevier
Unstable and unpredictable environments are linked to risk for psychopathology, but the
underlying neural mechanisms that explain how instability relate to subsequent mental …

Leveraging the developmental neuroscience of caregiving to promote resilience among youth exposed to adversity

DG Gee, EM Cohodes - Development and psychopathology, 2023 - cambridge.org
Early adversity is a major risk factor for the emergence of psychopathology across
development. Identifying mechanisms that support resilience, or favorable mental health …