Risk factors of severe COVID-19: a review of host, viral and environmental factors
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …
asymptomatic infections to severe disease and death. Understanding the risk factors of …
Immunosenescence and inflamm-ageing in COVID-19
The destructive effects of coronavirus disease 2019 (COVID-19) on the elderly and people
with cardiovascular disease have been proven. New findings shed light on the role of aging …
with cardiovascular disease have been proven. New findings shed light on the role of aging …
Predictive performance and clinical application of COV50, a urinary proteomic biomarker in early COVID-19 infection: a prospective multicentre cohort study
JA Staessen, R Wendt, YL Yu, S Kalbitz… - The Lancet Digital …, 2022 - thelancet.com
Summary Background The SARS-CoV-2 pandemic is a worldwide challenge. The CRIT-
CoV-U pilot study generated a urinary proteomic biomarker consisting of 50 peptides …
CoV-U pilot study generated a urinary proteomic biomarker consisting of 50 peptides …
Circulating extracellular particles from severe COVID-19 patients show altered profiling and innate lymphoid cell-modulating ability
Introduction Extracellular vesicles (EVs) and particles (EPs) represent reliable biomarkers
for disease detection. Their role in the inflammatory microenvironment of severe COVID-19 …
for disease detection. Their role in the inflammatory microenvironment of severe COVID-19 …
[HTML][HTML] Recent developments in frailty identification, management, risk factors and prevention: A narrative review of leading journals in geriatrics and gerontology
Frailty is an age-related clinical condition characterised by an increased susceptibility to
stressors and an elevated risk of adverse outcomes such as mortality. In the light of global …
stressors and an elevated risk of adverse outcomes such as mortality. In the light of global …
Rate of COVID‐19 vaccination among patients with cancer who tested positive for severe acute respiratory syndrome‐coronavirus 2: Analysis of the American Society …
D Kurbegov, SS Bruinooge, XJ Lei, MK Kirkwood… - Cancer, 2023 - Wiley Online Library
Background The availability of safe and effective COVID‐19 vaccines has enabled
protections against serious COVID‐19 outcomes, which are particularly important for …
protections against serious COVID‐19 outcomes, which are particularly important for …
Chromogranin A plasma levels predict mortality in COVID-19
R De Lorenzo, C Sciorati, GA Ramirez, B Colombo… - PLoS …, 2022 - journals.plos.org
Background Chromogranin A (CgA) and its fragment vasostatin I (VS-I) are secreted in the
blood by endocrine/neuroendocrine cells and regulate stress responses. Their involvement …
blood by endocrine/neuroendocrine cells and regulate stress responses. Their involvement …
Mortality from all-cause and cause-specific in the elderly: Joint implications of anemia and frailty
HR Zhang, X Wei, XT Chen, XD Sun - Archives of gerontology and geriatrics, 2023 - Elsevier
Background Anemia is prevalent among older adults, and it contributes to the incidence of
frailty. In turn, the frail elderly may be deficient in nutrients, including iron, vitamin B-12, and …
frailty. In turn, the frail elderly may be deficient in nutrients, including iron, vitamin B-12, and …
Association between SUMF1 polymorphisms and COVID-19 severity
S Liang, H Gao, T He, L Li, X Zhang, L Zhao, J Chen… - BMC Genomic …, 2023 - Springer
Background Evidence shows that genetic factors play important roles in the severity of
coronavirus disease 2019 (COVID-19). Sulfatase modifying factor 1 (SUMF1) gene is …
coronavirus disease 2019 (COVID-19). Sulfatase modifying factor 1 (SUMF1) gene is …
Frailty and risk of hospitalization from COVID-19 infection among older adults: evidence from the Dutch Lifelines COVID-19 Cohort study
Background Frailty is associated with COVID-19 severity in clinical settings. No general
population-based studies on the association between actual frailty status and COVID-19 …
population-based studies on the association between actual frailty status and COVID-19 …