[HTML][HTML] The evolution of aging and lifespan

S Li, JM Vazquez, PH Sudmant - Trends in Genetics, 2023 - cell.com
Aging is a nearly inescapable trait among organisms yet lifespan varies tremendously
across different species and spans several orders of magnitude in vertebrates alone. This …

Hallmarks of totipotent and pluripotent stem cell states

P Du, J Wu - Cell Stem Cell, 2024 - cell.com
Though totipotency and pluripotency are transient during early embryogenesis, they
establish the foundation for the development of all mammals. Studying these in vivo has …

Host traits shape virome composition and virus transmission in wild small mammals

YM Chen, SJ Hu, XD Lin, JH Tian, JX Lv, MR Wang… - Cell, 2023 - cell.com
Bats, rodents, and shrews are the most important animal sources of human infectious
diseases. However, the evolution and transmission of viruses among them remain largely …

Bat species assemblage predicts coronavirus prevalence

M Meyer, DW Melville, HJ Baldwin, K Wilhelm… - Nature …, 2024 - nature.com
Anthropogenic disturbances and the subsequent loss of biodiversity are altering species
abundances and communities. Since species vary in their pathogen competence, spatio …

Endogenous retroviruses in development and health

J Wang, X Lu, W Zhang, GH Liu - Trends in Microbiology, 2023 - cell.com
Endogenous retroviruses (ERVs) are evolutionary remnants of retroviral infections in which
the viral genome became embedded as a dormant regulatory element within the host …

Efficient derivation of transgene-free porcine induced pluripotent stem cells enables in vitro modeling of species-specific developmental timing

JV Conrad, S Meyer, PS Ramesh, JA Neira… - Stem Cell Reports, 2023 - cell.com
Sus scrofa domesticus (pig) has served as a superb large mammalian model for biomedical
studies because of its comparable physiology and organ size to humans. The derivation of …

The translational potential of studying bat immunity

K Baid, AT Irving, N Jouvenet, A Banerjee - Trends in Immunology, 2024 - cell.com
Molecular studies in bats have led to the discovery of antiviral adaptations that may explain
how some bat species have evolved enhanced immune tolerance towards viruses …

[HTML][HTML] Immunological features of bats: resistance and tolerance to emerging viruses

WL Demian, O Cormier, K Mossman - Trends in Immunology, 2024 - cell.com
Bats are among the most diverse mammalian species, representing over 20% of mammalian
diversity. The past two decades have witnessed a disproportionate spillover of viruses from …

Jump-starting life: balancing transposable element co-option and genome integrity in the developing mammalian embryo

ME Oomen, ME Torres-Padilla - EMBO reports, 2024 - embopress.org
Remnants of transposable elements (TEs) are widely expressed throughout mammalian
embryo development. Originally infesting our genomes as selfish elements and acting as a …

Establishment of African pygmy mouse induced pluripotent stem cells using defined doxycycline inducible transcription factors

S Matsuya, K Fujino, H Imai, KT Kusakabe, W Fujii… - Scientific Reports, 2024 - nature.com
Mus minutoides is one of the smallest mammals worldwide; however, the regulatory
mechanisms underlying its dwarfism have not been examined. Therefore, we aimed to …