Vascular dementia (VaD) is the second most common type of dementia. VaD is synonymous
with ageing, and its symptoms place a significant burden on the health and wellbeing of …

Background Advanced maternal age is currently a term defined by chronological age.
However, a group of biomarkers known as epigenetic clocks, which can predict morbidity …

This comprehensive review explores the emerging field of epigenetics in intracranial
aneurysm (IA) and aneurysmal subarachnoid hemorrhage (aSAH). Despite recent …

Alcohol dependence poses a global health threat associated with aging and reduced life
expectancy. Recently, aging research through deoxyribonucleic acid (DNA) methylation has …

The continued development in methylome analysis has enabled a more precise assessment
of DNA methylation, but treatment of target tissue prior to analysis may affect DNA analysis …

Background Thiopurine methyltransferase (TPMT) is a crucial enzyme for azathioprine
biotransformation and its activity is higher in very early onset inflammatory bowel disease …

Background: Genetic and epigenetic changes, oxidative stress and inflammation influence
the rate of aging, which diseases, lifestyle and environmental factors can further accelerate …

Objectives This study examined associations of childhood police encounters with biological
age acceleration in later life, and their mediation by subjective or objective social isolation …

In an effort to elucidate new factors that may contribute to developmental psychopathology,
the current study examined whether accelerated epigenetic aging at birth related to …

STUDY QUESTION Are markers of epigenetic age acceleration in follicular fluid associated
with outcomes of ovarian stimulation? SUMMARY ANSWER Increased epigenetic age …