Background Development of in vivo biomarkers has shifted the diagnosis of Alzheimer's
disease (AD) from the later dementia stages of disease towards the earlier stages and has …

Limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-
NC) and Alzheimer's disease neuropathologic change (ADNC) are each associated with …

Alzheimer's disease (AD) is an incurable, progressive neurodegenerative disorder. AD is a
complex and multifactorial disease that is responsible for 60–80% of dementia cases. Aging …

Dementia is the most common neurodegenerative disorder globally. Disease progression is
marked by declining cognitive function accompanied by changes in mobility. Increased …

A growing body of evidence has demonstrated a link between Alzheimer disease (AD) and
epilepsy. Late-onset epilepsy and epileptiform activity can precede cognitive deterioration in …

The amyloid cascade hypothesis for Alzheimer's disease is still alive, although heavily
challenged. Effective anti-amyloid immunotherapy would confirm the hypothesis' claim that …

The neuropathological hallmarks of Alzheimer's disease (AD), Parkinson's disease (PD),
frontotemporal lobar degeneration (FTLD), and amyotrophic lateral sclerosis (ALS) are …

Sustained exposures to ubiquitous outdoor/indoor fine particulate matter (PM2. 5), including
combustion and friction ultrafine PM (UFPM) and industrial nanoparticles (NPs) starting in …

Sex-specific differences in biology and physiology likely start at the time of conception and
progress and mature during the pre-puberty time frame and then during the transitions …

Neurodegenerative diseases such as Parkinson's (PD) and Alzheimer's disease (AD), the
prevalence of which is rapidly rising due to an aging world population and westernization of …