A comprehensive review of viral characteristics, transmission, pathophysiology, immune response, and management of SARS-CoV-2 and COVID-19 as a basis for …

CR Triggle, D Bansal, H Ding, MM Islam… - Frontiers in …, 2021 - frontiersin.org
COVID-19 emerged from China in December 2019 and during 2020 spread to every
continent including Antarctica. The coronavirus, SARS-CoV-2, has been identified as the …

[PDF][PDF] Dietary intervention with functional foods modulating gut microbiota for improving the efficacy of COVID-19 vaccines

S Oh, H Seo - Heliyon, 2023 - cell.com
Dysbiosis of the gut microbiota with aging contributes to a reduction in important cross-
feeding bacterial reactions in the gut and immunosenescence, which could contribute to a …

Lactate is associated with mortality in very old intensive care patients suffering from COVID-19: results from an international observational study of 2860 patients

RR Bruno, B Wernly, H Flaatten, J Fjølner… - Annals of intensive …, 2021 - Springer
Purpose Lactate is an established prognosticator in critical care. However, there still is
insufficient evidence about its role in predicting outcome in COVID-19. This is of particular …

[HTML][HTML] How severe acute respiratory syndrome coronavirus-2 aerosol propagates through the age-specific upper airways

MS Islam, P Larpruenrudee, SC Saha… - Physics of …, 2021 - pubs.aip.org
The recent outbreak of the COVID-19 causes significant respirational health problems,
including high mortality rates worldwide. The deadly corona virus-containing aerosol enters …

Insufficient epitope-specific T cell clones are responsible for impaired cellular immunity to inactivated SARS-CoV-2 vaccine in older adults

C Xiao, Z Ren, B Zhang, L Mao, G Zhu, L Gao, J Su… - Nature Aging, 2023 - nature.com
Aging is a critical risk factor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) vaccine efficacy. The immune responses to inactivated vaccine for older adults, and the …

The association of the Activities of Daily Living and the outcome of old intensive care patients suffering from COVID-19

RR Bruno, B Wernly, H Flaatten, J Fjølner… - Annals of intensive …, 2022 - Springer
Purpose Critically ill old intensive care unit (ICU) patients suffering from Sars-CoV-2 disease
(COVID-19) are at increased risk for adverse outcomes. This post hoc analysis investigates …

Immune Responses against SARS-CoV-2—Questions and Experiences

H Mangge, M Kneihsl, W Schnedl, G Sendlhofer… - Biomedicines, 2021 - mdpi.com
Understanding immune reactivity against SARS-CoV-2 is essential for coping with the
COVID-19 pandemic. Herein, we discuss experiences and open questions about the …

Shining a spotlight: the ramifications of the COVID-19 pandemic for older adults

EA Miller - The COVID-19 Pandemic and Older Adults, 2022 - taylorfrancis.com
The COVID-19 pandemic has disrupted life globally through virus-related mortality and
morbidity and the social and economic impacts of actions taken to stop the virus' spread. It …

Remdesivir, renal function and short-term clinical outcomes in elderly COVID-19 pneumonia patients: A single-centre study

E Biancalana, M Chiriacò, P Sciarrone… - … Interventions in Aging, 2021 - Taylor & Francis
Background Remdesivir, an antiviral agent able to reduce inflammatory cascade
accompanying severe, life-threatening pneumonia, became the first drug approved by the …

Incidence, severity and outcomes of COVID-19 in age and gender matched adults with and without epilepsy in Moscow: A historical cohort study

F Rider, WA Hauser, A Yakovlev, A Shpak… - … : European Journal of …, 2023 - Elsevier
Objective We hypothesized that PWE have an increased risk to acquire COVID-19. This was
a historical cohort study to determine COVID-19 incidence, severity, mortality and risk factors …