In the context of accelerated aging of the population worldwide, frailty has emerged as one
of the main risk factors that can lead to loss of self-sufficiency in older people. This syndrome …

Global population aging poses a tremendous burden on the health care system worldwide.
Frailty is associated with decreased physical reserve and is considered an important …

Background Residents and staff in long-term care facilities have been prioritised for
vaccination against SARS-CoV-2, but data on potential waning of vaccine effectiveness and …

Background Successive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variants have caused severe disease in long-term care facility (LTCF) residents. Primary …

VIVALDI (ISRCTN14447421) is a government-funded longitudinal open observational
cohort study of staff and residents in care homes for older people in England. The study …

General population studies have shown strong humoral response following severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination with subsequent waning of …

Objective To describe the prevalence of potentially clinically relevant gut pathogens and
associations with the carriage of resistant organisms in UK care home residents. Methods …

Simple Summary Receiving a diagnosis of cancer in older adults supersizes the coexisting
multimorbidity and frailty of the single individual. The multidimensional nature of this …

Objective To investigate the risk factors for major limb adverse events (MALE) in peripheral
arterial disease (PAD) combined with frailty and to develop and validate a risk prediction …

Background General population studies have shown strong humoral response following
SARS-CoV-2 vaccination with subsequent waning of anti-spike antibody levels. Vaccine …