Recurrent evolution of vertebrate transcription factors by transposase capture

RL Cosby, J Judd, R Zhang, A Zhong, N Garry… - Science, 2021 - science.org
INTRODUCTION How novel protein architectures evolve remains poorly understood. The
rearrangement of domains with preexisting functions into new composite architectures …

[PDF][PDF] Recurrent evolution of vertebrate transcription factors by transposase capture

RL Cosby, J Judd, R Zhang, A Zhong, N Garry… - public.websites.umich.edu
RESULTS: We used comparative genomics to survey all tetrapod genomes with available
gene models (596) for putative HTFs. We identified 106 distinct HTFs derived from 94 …

RECURRENT EVOLUTION OF VERTEBRATE TRANSCRIPTION FACTORS VIA TRANSPOSASE CAPTURE

RL Cosby - 2019 - ecommons.cornell.edu
Despite their vital role as regulators of gene expression, the evolutionary origin of
transcription factors (TFs) and the mechanisms by which new TFs evolve remain poorly …

Recurrent evolution of vertebrate transcription factors by transposase capture

RL Cosby, J Judd, R Zhang, A Zhong, N Garry… - paper.sciencenet.cn
Genes with novel cellular functions may evolve through exon shuffling, which can assemble
novel protein architectures. Here, we show that DNA transposons provide a recurrent supply …

Recurrent evolution of vertebrate transcription factors by transposase capture

RL Cosby, J Judd, R Zhang, A Zhong… - … (New York, NY), 2021 - pubmed.ncbi.nlm.nih.gov
Genes with novel cellular functions may evolve through exon shuffling, which can assemble
novel protein architectures. Here, we show that DNA transposons provide a recurrent supply …

Recurrent evolution of vertebrate transcription factors by transposase capture

RL Cosby, J Judd, R Zhang, A Zhong, N Garry… - Science, 2021 - cir.nii.ac.jp
抄録< jats: title> A recipe for new genes</jats: title>< jats: p> Most lineages contain
evolutionarily novel genes, but their origin is not always clear. Cosby< jats: italic> et al.</jats …

Recurrent evolution of vertebrate transcription factors by transposase capture

RL Cosby, J Judd, R Zhang, A Zhong, N Garry… - bioRxiv, 2020 - biorxiv.org
How genes with novel cellular functions evolve is a central biological question. Exon
shuffling is one mechanism to assemble new protein architectures. Here we show that DNA …

[PDF][PDF] Recurrent evolution of vertebrate transcription factors by transposase capture 2

RL Cosby, J Judd, R Zhang, A Zhong, N Garry - scholar.archive.org
How genes with novel cellular functions evolve is a central biological question. Exon 15
shuffling is one mechanism to assemble new protein architectures. Here we show that DNA …

Recurrent evolution of vertebrate transcription factors by transposase capture.

RL Cosby, J Judd, R Zhang, A Zhong… - Science (New York …, 2021 - europepmc.org
Genes with novel cellular functions may evolve through exon shuffling which can assemble
unique protein architectures. Here we show that DNA transposons provide a recurrent …

[HTML][HTML] Recurrent evolution of vertebrate transcription factors by transposase capture

RL Cosby, J Judd, R Zhang, A Zhong… - Science (New York …, 2021 - ncbi.nlm.nih.gov
Genes with novel cellular functions may evolve through exon shuffling which can assemble
unique protein architectures. Here we show that DNA transposons provide a recurrent …