Precision oncology seeks to leverage molecular information about cancer to improve patient
outcomes. Tissue biopsy samples are widely used to characterize tumours but are limited by …

Precision medicine refers to the choosing of targeted therapies based on genetic data. Due
to the increasing availability of data from large-scale tumor genome sequencing projects …

Liquid biopsy is a technique that utilizes circulating biomarkers in the body fluids of cancer
patients to provide information regarding the genetic landscape of the cancer. It is emerging …

Molecular characterization of a patient's tumor to guide treatment decisions is increasingly
being applied in clinical care and can have a significant impact on disease outcome. These …

The inherent molecular heterogeneity of metastatic tumors and the ability of cancer
genomes to dynamically evolve are not properly captured by tissue specimens. Analysis of …

Current molecular diagnostics in cancer patients is based on needle biopsies, which,
however, face serious limitations which can lead to false decisions. Individual tumors consist …

Precision oncology aims to tailor clinical decisions specifically to patients with the objective
of improving treatment outcomes. This can be achieved by leveraging omics information for …

The minimally—or non-invasive detection of circulating tumor-derived components in
biofluids, such as blood, liquid biopsy is a revolutionary approach with significant potential …

Editorial summary Progress in sensitive analytical approaches has opened new avenues for
the detection of cells or products such as circulating cell-free DNA released by tumors …

Over the last decades, the concept of precision medicine has dramatically renewed the field
of medical oncology; the introduction of patient-tailored therapies has significantly improved …