As the size of genome-wide association studies increase, the number of associated trait loci
identified inevitably increase. One welcomes this if it allows the better delineation of the …

Genome-wide association studies (GWAS) have gained considerable momentum over the
last couple of years for the identification of novel complex disease genes. In the field of …

Alzheimer's disease is a progressive neurodegenerative disorder with high prevalence in
old age. It is the most common cause of dementia, with a risk reaching 50% after the age of …

Background Alzheimer's disease is a debilitating and highly heritable neurological
condition. As such, genetic studies have sought to understand the genetic architecture of …

More than 20 genetic loci have been associated with risk for Alzheimer's disease (AD), but
reported genome-wide significant loci do not account for all the estimated heritability and …

Alzheimer's disease (AD) is highly heritable and recent studies have identified over 20
disease-associated genomic loci. Yet these only explain a small proportion of the genetic …

Genome-wide association studies (GWASs) have revealed a plethora of putative
susceptibility genes for Alzheimer's disease (AD). With the sole exception of the APOE gene …

Background Alzheimer's disease (AD) is a complex multifactorial neurodegenerative
disorder and the most common form of dementia. AD is highly heritable, with heritability …

The risk of Alzheimer's disease (AD) is strongly determined by genetic factors and recent
genome-wide association studies (GWAS) have identified several genes for the disease risk …

The past decade has witnessed hundreds of reports declaring or refuting genetic
association with putative Alzheimer disease susceptibility genes. This wealth of information …