[HTML][HTML] Identification of ULK1 as a novel mitophagy-related gene in diabetic nephropathy

YY Yang, ZX Gao, ZH Mao, DW Liu, ZS Liu… - Frontiers in …, 2023 - frontiersin.org
Background Accumulating evidence indicates that mitophagy is crucial for the development
of diabetic nephropathy (DN). However, little is known about the key genes involved. The …

[HTML][HTML] GBP2 promotes M1 macrophage polarization by activating the notch1 signaling pathway in diabetic nephropathy

X Li, J Liu, M Zeng, K Yang, S Zhang, Y Liu… - Frontiers in …, 2023 - frontiersin.org
Background Diabetic nephropathy (DN) is one of the most common diabetic complications,
which has become the primary cause of end-stage renal disease (ESRD) globally …

[HTML][HTML] Identification of hub genes and immune-related pathways for membranous nephropathy by bioinformatics analysis

XY Cai, ZF Wang, SW Ge, G Xu - Frontiers in Physiology, 2022 - frontiersin.org
OBJECTIVE: We aim to explore the detailed molecular mechanisms of membrane
nephropathy (MN) related genes by bioinformatics analysis. METHODS: Two microarray …

[HTML][HTML] Bioinformatics analysis reveals crosstalk among platelets, immune cells, and the glomerulus that may play an important role in the development of diabetic …

X Yao, H Shen, F Cao, H He, B Li, H Zhang… - Frontiers in …, 2021 - frontiersin.org
Diabetic nephropathy (DN) is the main cause of end stage renal disease (ESRD).
Glomerulus damage is one of the primary pathological changes in DN. To reveal the gene …

[HTML][HTML] Identification and validation of immune and oxidative stress-related diagnostic markers for diabetic nephropathy by WGCNA and machine learning

M Xu, H Zhou, P Hu, Y Pan, S Wang, L Liu… - Frontiers in …, 2023 - frontiersin.org
Background Diabetic nephropathy (DN) is the primary cause of end-stage renal disease, but
existing therapeutics are limited. Therefore, novel molecular pathways that contribute to DN …

[HTML][HTML] Identification of VCAN as hub gene for diabetic kidney disease immune injury using integrated bioinformatics analysis

Q Xu, B Li, Y Wang, C Wang, S Feng, L Xue… - Frontiers in …, 2021 - frontiersin.org
Background: Diabetic kidney disease (DKD) is a leading cause of chronic kidney disease in
China. Tubular injury contributes to the progression of DKD. Our study was conducted to …

[HTML][HTML] Integrative analyses of biomarkers and pathways for diabetic nephropathy

B Li, X Zhao, W Xie, Z Hong, Y Zhang - Frontiers in Genetics, 2023 - frontiersin.org
Background: Diabetic nephropathy (DN) is a widespread diabetic complication and a major
cause of terminal kidney disease. There is no doubt that DN is a chronic disease that …

Epidermal growth factor receptor and podocin predict nephropathy progression in type 2 diabetic patients through interaction with the autophagy influencer ULK-1

AAA El-Shazly, AM Sallam, MH El-Hefnawy… - Journal of Diabetes and …, 2019 - Elsevier
Aims Diabetic nephropathy (DN) that progress to end stage renal failure is a serious health
problem. Autophagy is involved in DN pathogenesis. Finding renal prognostic biomarkers …

[HTML][HTML] Identification of hub genes and potential ceRNA networks of diabetic nephropathy by weighted gene Co-expression network analysis

G Li, J Zhang, D Liu, Q Wei, H Wang, Y Lv, Z Ye… - Frontiers in …, 2021 - frontiersin.org
Diabetic nephropathy (DN) is one of the most common microvascular complications in
diabetic patients, and is the main cause of end-stage renal disease. The exact molecular …

[HTML][HTML] Single-cell RNA and transcriptome sequencing profiles identify immune-associated key genes in the development of diabetic kidney disease

X Zhang, P Chao, L Zhang, L Xu, X Cui… - Frontiers in …, 2023 - frontiersin.org
Background There is a growing public concern about diabetic kidney disease (DKD), which
poses a severe threat to human health and life. It is important to discover noninvasive and …