Effect of cholecalciferol supplementation on the clinical features and inflammatory markers in hospitalized COVID-19 patients: a randomized, open-label, single-center …

TL Karonova, KA Golovatyuk, IV Kudryavtsev… - Nutrients, 2022 - mdpi.com
Recent studies showed that a low 25-hydroxyvitamin D (25 (OH) D) level was associated
with a higher risk of morbidity and severe course of COVID-19. Our study aimed to evaluate …

Influence of 25-hydroxy-cholecalciferol levels on SARS-CoV-2 infection and COVID-19 severity: A systematic review and meta-analysis

A Crafa, R Cannarella, RA Condorelli… - …, 2021 - thelancet.com
Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the
etiological agent of coronavirus disease 19 (COVID-19), a respiratory infection that, starting …

[HTML][HTML] High-dose cholecalciferol booster therapy is associated with a reduced risk of mortality in patients with COVID-19: a cross-sectional multi-centre observational …

SF Ling, E Broad, R Murphy, JM Pappachan… - Nutrients, 2020 - mdpi.com
The worldwide pandemic of 2019 novel coronavirus disease (COVID-19) has posed the
most substantial and severe public health issue for several generations, and therapeutic …

Is there a crucial link between vitamin D status and inflammatory response in patients with COVID-19?

F Saponaro, M Franzini, C Okoye, R Antognoli… - Frontiers in …, 2022 - frontiersin.org
Background Hypovitaminosis D has been suggested to play a possible role in coronavirus
disease 2019 (COVID-19) infection. Methods The aim of this study is to analyze the …

[HTML][HTML] Changes in the immune response against SARS-CoV-2 in individuals with severe COVID-19 treated with high dose of vitamin D

M Torres, G Casado, L Vigón, S Rodríguez-Mora… - Biomedicine & …, 2022 - Elsevier
Main cause of severe illness and death in COVID-19 patients appears to be an excessive
but ineffectual inflammatory immune response that may cause severe acute respiratory …

[HTML][HTML] Vitamin D sufficiency, a serum 25-hydroxyvitamin D at least 30 ng/mL reduced risk for adverse clinical outcomes in patients with COVID-19 infection

Z Maghbooli, MA Sahraian, M Ebrahimi, M Pazoki… - PloS one, 2020 - journals.plos.org
Background To investigate the association between serum 25-hydroxyvitamin D levels and
its effect on adverse clinical outcomes, and parameters of immune function and mortality due …

A single-oral bolus of 100,000 IU of cholecalciferol at hospital admission did not improve outcomes in the COVID-19 disease: the COVID-VIT-D—a randomised …

JB Cannata-Andía, A Díaz-Sottolano, P Fernández… - BMC medicine, 2022 - Springer
Background Vitamin D status has been implicated in COVID-19 disease. The objective of the
COVID-VIT-D trial was to investigate if an oral bolus of cholecalciferol (100,000 IU) …

Beneficial Effect of Short-Term Supplementation of High Dose of Vitamin D3 in Hospitalized Patients With COVID-19: A Multicenter, Single-Blinded, Prospective …

M Cervero, D López-Wolf, G Casado… - Frontiers in …, 2022 - frontiersin.org
There is now sufficient evidence to support that vitamin D deficiency may predispose to
SARS-CoV-2 infection and increase COVID-19 severity and mortality. It has been suggested …

The effects of high dose vitamin D supplementation as a nutritional intervention strategy on biochemical and inflammatory factors in adults with COVID-19: Study …

Z Khorasanchi, A Jafazadeh Esfehani… - Nutrition and …, 2022 - journals.sagepub.com
Introduction: Low serum vitamin D has been shown to be a risk factor for Coronavirus 2019
(COVID-19). The aim of this study was to assess the effects of high dose vitamin D …

Analysis of vitamin D level among asymptomatic and critically ill COVID-19 patients and its correlation with inflammatory markers

A Jain, R Chaurasia, NS Sengar, M Singh, S Mahor… - Scientific reports, 2020 - nature.com
COVID-19 is characterized by marked variability in clinical severity. Vitamin D had recently
been reviewed as one of the factors that may affect the severity in COVID-19. The objective …