Background Glioblastoma multiforme (GBM) is the most common cancer of the central
nervous system, while Parkinson's disease (PD) is a degenerative neurological condition …

Objective: To investigate the local immune status and its prognostic value in glioma.
Methods: A cohort of 297 glioma samples with whole genome microarray expression data …

Background: Head and neck squamous cell carcinoma (HNSCC) is the seventh most
common type of cancer worldwide. Its highly aggressive and heterogeneous nature and …

Background Glioblastoma multiforme (GBM) is extensively genetically and transcriptionally
heterogeneous, which poses challenges for classification and management. Long …

Glioma is the most common and fatal primary brain tumor in human. Long non-coding RNA
(lncRNA), which are characterized by regulation of gene expression and chromatin …

Purpose Glioblastoma (GBM) is the most common primary brain tumor in adults and is
notorious for its lethality. Given its limited therapeutic measures and high heterogeneity, the …

Background The immunotherapy of Glioma has always been a research hotspot. Although
tumor associated microglia/macrophages (TAMs) proves to be important in glioma …

Glioblastoma (GBM) is resistant to multimodality therapeutic approaches. A high burden of
tumor-specific mutant peptides (neoantigens) correlates with better survival and response to …

Glioblastoma (GBM) is the most common type of malignant tumor of the central nervous
system. The prognosis of patients with GBM is very poor, with a survival time of~ 15 months …

Recent work has highlighted the tumor microenvironment as a central player in cancer. In
particular, interactions between tumor and immune cells may help drive the development of …