Formulation, characterization, pharmacokinetics and antioxidant activity of phloretin oral granules

RD Deshpande, DS Shah, S Gurram, DK Jha… - International Journal of …, 2023 - Elsevier
Phloretin (PHL), a flavonoid of the dihydrogen chalcone class, is reported to have low oral
bioavailability due to its poor solubility and absorption. A common approach to enhance the …

Development and evaluation of PLGA polymer based nanoparticles of quercetin

MK Anwer, MA Al-Mansoor, S Jamil… - International journal of …, 2016 - Elsevier
Quercetin is the most abundant antioxidant found in the human diet. Low aqueous solubility
of quercetin limits its bioavailability and hence therapeutic effects. Therefore, the aim of the …

Novel formulation strategy to enhance solubility of quercetin

PN Kendre, VV Pande, KM Chavan - Pharmacophore, 2014 - pharmacophorejournal.com
The aim of present study to enhance the solubility of quercetin, a poorly water soluble drug,
quercetin containing blends (keeping total concentration 40% w/v, constant) was fabricated …

[HTML][HTML] Development and optimization of quercetin-loaded PLGA nanoparticles by experimental design

LR Tefas, I Tomuţă, M Achim, L Vlase - Clujul Medical, 2015 - ncbi.nlm.nih.gov
Materials and methods The nanoparticles were prepared by the nanoprecipitation method. A
3-factor, 3-level Box-Behnken design was employed in this study considering poly (D, L …

Hesperetin loaded proposomal gel for topical antioxidant activity

VM Vaz, SR Jitta, R Verma, L Kumar - Journal of Drug Delivery Science and …, 2021 - Elsevier
The present study was aimed at formulating and evaluating hesperetin-loaded proposomal
gel for topical antioxidant activity. Hesperetin-loaded proposomes were first formulated and …

[HTML][HTML] Antioxidant activity and hemocompatibility study of quercetin loaded plga nanoparticles

S Derman, D Uzunoglu, T Acar, T Arasoglu… - Iranian Journal of …, 2020 - ncbi.nlm.nih.gov
Quercetin (QU) is an important flavonoid compound presenting lots of biological activities,
but its application has been limited due to its low aqueous solubility and instability. In this …

Formulation and in vitro evaluation of hesperidin-phospholipid complex and its antioxidant potential

B Kalita, BN Patwary - Current Drug Therapy, 2020 - ingentaconnect.com
Background: The recent trend of herbal drug delivery has been focused on developing novel
drug delivery carriers to address problems related to solubility, oral bioavailability, skin …

[PDF][PDF] Quality by design based quercetin hydrate nanoemulsions for enhanced solubility by reducing particle size

LS Kumar, HA Ahad - Ind. J. Pharm. Edu. Res, 2023 - ijper.org
ABSTRACT Aim/Background: The oral-based drug delivery system has a great pace in this
era of novel discoveries. The globe is running toward new medical dosage forms, but from …

Quality by design-based optimization of formulation parameters to develop quercetin nanosuspension for improving its biopharmaceutical properties

OA Alsaidan, P Pattanayak, A Awasthi… - South African Journal of …, 2022 - Elsevier
The present study describes the formulation, optimization and characterization of quercetin
loaded nanosuspension. The formulation was prepared using liquid antisolvent precipitation …

Enhancement of solubility and dissolution rate of quercetin with solid dispersion system formation using hydroxypropyl methyl cellulose matrix

D Setyawan, AA Fadhil, D Juwita… - Thai Journal of …, 2017 - repository.unair.ac.id
Purpose: The aim of the present study was to obtain raw quercetin materials using solid
dispersion system with better solubility and dissolution rate than pure quercetin. Methods …