Alterations in hypothalamic–pituitary–adrenal (HPA) axis and its effector hormone cortisol
have been proposed as one possible mechanism linking child maltreatment experiences to …

BackgroundThis study investigates the impact of childhood maltreatment (CM) on
hypothalamic–pituitary–adrenal (HPA)-axis functioning and on anxiety perception …

Childhood maltreatment represents a significant risk factor for the development of a number
of mental and physical health outcomes. Converging evidence suggests that early adversity …

Rationale Abuse and neglect are highly prevalent in children and have enduring
neurobiological effects. Stressful early life environments perturb the hypothalamic–pituitary …

Background Alterations of the development of the hypothalamic-pituitary-adrenal axis
(HPAA) have been suggested to be related to experiences of early maltreatment. It has been …

Objective Child maltreatment is associated with dysregulation of stress-mediating systems
and an increased risk of mental and physical health problems. Specifically, disruptions in …

Childhood maltreatment leads to a host of negative physical and mental health outcomes,
with cortisol dysregulation implicated as a possible mechanism. Given inconsistencies …

OBJETIVO: A meta deste artigo foi a de estudar as relações ente maus-tratos na infância e
psicopatologia no adulto, como reflexo de uma disfunção do eixo hipotálamo-pituitária …

The neurobiological mechanisms by which childhood maltreatment heightens vulnerability
to psychopathology remain poorly understood. It is likely that a complex interaction between …

There is a relative consensus about the detrimental impact of childhood maltreatment on
later mental health problems and behavioral difficulties. Prior research suggests that …