Biomolecular condensates are membraneless intracellular assemblies that often form via
liquid− liquid phase separation and have the ability to concentrate biopolymers. Research …

The intracellular environment is partitioned into functionally distinct compartments
containing specific sets of molecules and reactions. Biomolecular condensates, also …

Biomolecular condensate formation has been implicated in a host of biological processes
and has found relevance in biology and disease. Understanding the physical principles and …

Protein aggregation is a feature of numerous neurodegenerative diseases. However,
regulated, often reversible, formation of protein aggregates, also known as condensates …

Phase separation and transition control the assembly and material states (liquid, gel like, or
solid) of protein condensates to ensure that distinct cellular functions occur in a …

Motions in biomolecules are critical for biochemical reactions. In cells, many biochemical
reactions are executed inside of biomolecular condensates formed by ultradynamic …

In the past decade, membraneless assemblies known as biomolecular condensates have
been reported to play key roles in many cellular functions by compartmentalizing specific …

BACKGROUND Living cells contain distinct subcompartments to facilitate spatiotemporal
regulation of biological reactions. In addition to canonical membrane-bound organelles such …

Biomolecular condensates formed by the process of liquid–liquid phase separation (LLPS)
play diverse roles inside cells, from spatiotemporal compartmentalisation to speeding up …

Condensed states of proteins, including liquid-like membraneless organelles and solid-like
aggregates, contribute in fundamental ways to the organisation and function of the cell …