Comprehensive molecular characterization of muscle-invasive bladder cancer
We report a comprehensive analysis of 412 muscle-invasive bladder cancers characterized
by multiple TCGA analytical platforms. Fifty-eight genes were significantly mutated, and the …
by multiple TCGA analytical platforms. Fifty-eight genes were significantly mutated, and the …
An integrated multi-omics analysis identifies prognostic molecular subtypes of non-muscle-invasive bladder cancer
SV Lindskrog, F Prip, P Lamy, A Taber… - Nature …, 2021 - nature.com
The molecular landscape in non-muscle-invasive bladder cancer (NMIBC) is characterized
by large biological heterogeneity with variable clinical outcomes. Here, we perform an …
by large biological heterogeneity with variable clinical outcomes. Here, we perform an …
[HTML][HTML] A consensus molecular classification of muscle-invasive bladder cancer
Background Muscle-invasive bladder cancer (MIBC) is a molecularly diverse disease with
heterogeneous clinical outcomes. Several molecular classifications have been proposed …
heterogeneous clinical outcomes. Several molecular classifications have been proposed …
Prognostic power of a tumor differentiation gene signature for bladder urothelial carcinomas
Background Muscle-invasive bladder cancers (MIBCs) cause approximately 150 000 deaths
per year worldwide. Survival for MIBC patients is heterogeneous, with no clinically validated …
per year worldwide. Survival for MIBC patients is heterogeneous, with no clinically validated …
Molecular profiling in muscle‐invasive bladder cancer: more than the sum of its parts
Bladder cancers are biologically and clinically heterogeneous. Recent large‐scale
transcriptomic profiling studies focusing on life‐threatening muscle‐invasive cases have …
transcriptomic profiling studies focusing on life‐threatening muscle‐invasive cases have …
Comprehensive transcriptional analysis of early-stage urothelial carcinoma
J Hedegaard, P Lamy, I Nordentoft, F Algaba, S Høyer… - Cancer cell, 2016 - cell.com
Non-muscle-invasive bladder cancer (NMIBC) is a heterogeneous disease with widely
different outcomes. We performed a comprehensive transcriptional analysis of 460 early …
different outcomes. We performed a comprehensive transcriptional analysis of 460 early …
[HTML][HTML] Multi‐omics consensus ensemble refines the classification of muscle‐invasive bladder cancer with stratified prognosis, tumour microenvironment and distinct …
Dear Editor, The molecular classification of muscle-invasive bladder cancer (MIBC) based
on transcriptomic signatures has been extensively studied. 1–4 The complementary nature …
on transcriptomic signatures has been extensively studied. 1–4 The complementary nature …
Intrinsic basal and luminal subtypes of muscle-invasive bladder cancer
W Choi, B Czerniak, A Ochoa, X Su… - Nature Reviews …, 2014 - nature.com
Whole-genome analyses have revealed that muscle-invasive bladder cancers (MIBCs) are
heterogeneous and can be grouped into basal and luminal subtypes that are highly …
heterogeneous and can be grouped into basal and luminal subtypes that are highly …
EGFR as a potential therapeutic target for a subset of muscle-invasive bladder cancers presenting a basal-like phenotype
S Rebouissou, I Bernard-Pierrot… - Science translational …, 2014 - science.org
Muscle-invasive bladder carcinoma (MIBC) constitutes a heterogeneous group of tumors
with a poor outcome. Molecular stratification of MIBC may identify clinically relevant tumor …
with a poor outcome. Molecular stratification of MIBC may identify clinically relevant tumor …
Genomic predictors of good outcome, recurrence, or progression in high-grade t1 non–muscle-invasive bladder cancer
Abstract High-grade T1 (HGT1) bladder cancer is the highest risk subtype of non–muscle-
invasive bladder cancer with unpredictable outcome and poorly understood risk factors …
invasive bladder cancer with unpredictable outcome and poorly understood risk factors …