Alzheimer's disease (AD) is the most common neurodegenerative disease, with sporadic
form being the predominant type. Neuroinflammation plays a critical role in accelerating …

Neuroinflammation has been identified as another significant pathogenic factor in
Alzheimer's disease following Aβ amyloid deposition and tau protein hyperphosphorylation …

Trained immunity was recently discovered in innate immune cells and shown to facilitate the
clearance of pathogens at the time of occurrence of the second insult. However, it …

Traumatic brain injury (TBI) leads to lasting brain dysfunction with chronic
neuroinflammation typified by nucleotide-binding domain leucine-rich repeat and pyrin …

Alzheimer's disease (AD) is an irreversible neurodegenerative disorder that affects more
than 44 million people worldwide. Despite the high disease burden, there is no effective …

Background: Mesenchymal stem cells (MSCs)-derived extracellular vesicles (EVs) have
been reported to exhibit therapeutic effects in various animal models of neurological …

Mesenchymal stem-cell-derived small extracellular vesicles (MSC-EVs), as a therapeutic
agent, have shown great promise in the treatment of neurological diseases. To date, the …

Extracellular vesicles (EVs) released by human induced pluripotent stem cell-derived neural
stem cells (hiPSC-NSCs) are enriched with miRNAs and proteins capable of mediating …

Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive loss
of neurons in the brain. However, there are no effective drugs for AD. Mesenchymal stem …

Mesenchymal stromal/stem cells (MSCs) have great capacity for immune regulation. MSCs
provide protective paracrine effects, which are partially exerted by extracellular vesicles …