Drug resistance in cancer: mechanisms and tackling strategies

T Haider, V Pandey, N Banjare, PN Gupta… - Pharmacological …, 2020 - Springer
Drug resistance developed towards conventional therapy is one of the important reasons for
chemotherapy failure in cancer. The various underlying mechanism for drug resistance …

[HTML][HTML] The different mechanisms of cancer drug resistance: a brief review

B Mansoori, A Mohammadi, S Davudian… - Advanced …, 2017 - ncbi.nlm.nih.gov
Anticancer drugs resistance is a complex process that arises from altering in the drug
targets. Advances in the DNA microarray, proteomics technology and the development of …

Cancer drug resistance: A fleet to conquer

S Hussain, A Singh, SU Nazir, S Tulsyan… - Journal of cellular …, 2019 - Wiley Online Library
Cancer is a disease that claims millions of lives each year across the world. Despite
advancement in technologies and therapeutics for treating the disease, these modes are …

Cell signaling and cancer: a mechanistic insight into drug resistance

M Panda, BK Biswal - Molecular biology reports, 2019 - Springer
Drug resistance is a major setback for advanced therapeutics in multiple cancers. The
increasing prevalence of this resistance is a growing concern and bitter headache for the …

The challenge of drug resistance in cancer treatment: a current overview

M Nikolaou, A Pavlopoulou, AG Georgakilas… - Clinical & Experimental …, 2018 - Springer
It is generally accepted that recent advances in anticancer agents have contributed
significantly to the improvement of both the disease-free survival and quality of life in cancer …

[HTML][HTML] Drug resistance and combating drug resistance in cancer

X Wang, H Zhang, X Chen - Cancer drug resistance, 2019 - ncbi.nlm.nih.gov
Cancer is the second leading cause of death in the US. Current major treatments for cancer
management include surgery, cytotoxic chemotherapy, targeted therapy, radiation therapy …

Cancer chemoresistance; biochemical and molecular aspects: a brief overview

S Kachalaki, M Ebrahimi, LM Khosroshahi… - European journal of …, 2016 - Elsevier
The effectiveness of chemotherapy is one of the main challenges in cancer treatment and
resistance to classic drugs and traditional treatment processes is an obstacle to this goal …

Understanding and targeting resistance mechanisms in cancer

ZN Lei, Q Tian, QX Teng, JND Wurpel, L Zeng… - MedComm, 2023 - Wiley Online Library
Resistance to cancer therapies has been a commonly observed phenomenon in clinical
practice, which is one of the major causes of treatment failure and poor patient survival. The …

[HTML][HTML] The multi-molecular mechanisms of tumor-targeted drug resistance in precision medicine

X Li, M Li, M Huang, Q Lin, Q Fang, J Liu… - Biomedicine & …, 2022 - Elsevier
Clinically, cancer drug therapy is still dominated by chemotherapy drugs. Although the
emergence of targeted drugs has greatly improved the survival rate of patients with …

Dysregulated signalling pathways driving anticancer drug resistance

N Bou Antoun, AM Chioni - International journal of molecular sciences, 2023 - mdpi.com
One of the leading causes of death worldwide, in both men and women, is cancer. Despite
the significant development in therapeutic strategies, the inevitable emergence of drug …