[HTML][HTML] Revisiting the hallmarks of aging to identify markers of biological age

F Guerville, P De Souto Barreto, I Ader… - The Journal of …, 2020 - Springer
The Geroscience aims at a better understanding of the biological processes of aging, to
prevent and/or delay the onset of chronic diseases and disability as well as to reduce the …

Frailty biomarkers under the perspective of geroscience: a narrative review

RSSA Gonçalves, ÁCC Maciel, Y Rolland… - Ageing research …, 2022 - Elsevier
Cellular and molecular aging biomarkers might contribute to identify at-risk individuals for
frailty before overt clinical manifestations appear. Although studies on the associations of …

Promising biomarkers of human aging: In search of a multi-omics panel to understand the aging process from a multidimensional perspective

NA Rivero-Segura, OY Bello-Chavolla… - Ageing research …, 2020 - Elsevier
The aging process has been linked to the occurrence of chronic diseases and functional
impairments, including cancer, sarcopenia, frailty, metabolic, cardiovascular, and …

Healthy aging: the ultimate preventative medicine

M Kaeberlein, PS Rabinovitch, GM Martin - Science, 2015 - science.org
Age is the greatest risk factor for nearly every major cause of mortality in developed nations.
Despite this, most biomedical research focuses on individual disease processes without …

[图书][B] Biomarkers of human aging

A Moskalev - 2019 - Springer
In laboratory studies, potential geroprotective interventions have been created: more than
400 geroprotectors, several gene and cell therapies. Their translation into medical practice …

Advances in geroscience: impact on healthspan and chronic disease

JB Burch, AD Augustine, LA Frieden… - … Series A: Biomedical …, 2014 - academic.oup.com
Population aging is unprecedented, without parallel in human history, and the 21st century
will witness even more rapid aging than did the century just past. Improvements in public …

Measuring biological aging in humans: A quest

L Ferrucci, M Gonzalez‐Freire, E Fabbri… - Aging cell, 2020 - Wiley Online Library
The global population of individuals over the age of 65 is growing at an unprecedented rate
and is expected to reach 1.6 billion by 2050. Most older individuals are affected by multiple …

Moving geroscience from the bench to clinical care and health policy

F Sierra, A Caspi, RH Fortinsky… - Journal of the …, 2021 - Wiley Online Library
Geriatricians and others must embrace the emerging field of geroscience. Until recently
geroscience research was pursued in laboratory animals, but now this field requires …

[HTML][HTML] A proposed panel of biomarkers of healthy ageing

J Lara, R Cooper, J Nissan, AT Ginty, KT Khaw… - BMC medicine, 2015 - Springer
Background There is no criterion reference for assessing healthy ageing and this creates
difficulties when conducting and comparing research on ageing across studies. A cardinal …

The emergence of geroscience as an interdisciplinary approach to the enhancement of health span and life span

F Sierra - Cold Spring Harbor perspectives in …, 2016 - perspectivesinmedicine.cshlp.org
Research on the biology of aging has accelerated rapidly in the last two decades. It is now at
the point where translation of the findings into useful approaches to improve the health of the …