Background Liquid biopsy has emerged as a promising, non-invasive diagnostic approach
in oncology because the analysis of circulating tumor DNA (ctDNA) reflects the precise …

Abstract Analysis of the methylome of tumor cell-free deoxyribonucleic acid (DNA; cfDNA)
has emerged as a powerful non-invasive technique for cancer subtyping and prognosis …

Medulloblastoma (MB), the most common form of pediatric brain malignancy, has a low
frequency of oncogenic mutations but pronouncedly abnormal DNA methylation changes …

Liquid biopsies, in particular, analysis of cell-free DNA (cfDNA), have emerged as a
promising noninvasive diagnostic approach in oncology. Abnormal distribution of DNA …

Genome-wide DNA methylation profiling has shown that epigenetic abnormalities are
biologically important in glioma and can be used to classify these tumors into distinct …

Background The detection of somatic mutations in cell-free DNA (cfDNA) from liquid biopsy
has emerged as a noninvasive tool to monitor the follow-up of cancer patients. However, the …

Simple Summary Malignant liver tumors consist of primary tumors and metastases. A correct
diagnosis can be achieved with different methods; one of them is the analysis of the cell-free …

Background: Abnormal CpG methylation in cancer is ubiquitous and generally detected in
tumour specimens using a variety of techniques at a resolution encompassing single CpG …

Cell-free DNA (cfDNA) profiling as liquid biopsy has proven value in adult-onset
malignancies, serving as a patient-specific surrogate for residual disease and providing a …

Cancer continues to pose significant challenges to the medical community. Early detection,
accurate molecular profiling, and adequate assessment of treatment response are critical …