Histidine in health and disease: metabolism, physiological importance, and use as a supplement

M Holeček - Nutrients, 2020 - mdpi.com
L-histidine (HIS) is an essential amino acid with unique roles in proton buffering, metal ion
chelation, scavenging of reactive oxygen and nitrogen species, erythropoiesis, and the …

Histidine: A systematic review on metabolism and physiological effects in human and different animal species

J Moro, D Tomé, P Schmidely, TC Demersay… - Nutrients, 2020 - mdpi.com
Histidine is an essential amino acid (EAA) in mammals, fish, and poultry. We aim to give an
overview of the metabolism and physiological effects of histidine in humans and different …

Antioxidant characteristics of L-histidine

AM Wade, HN Tucker - The Journal of Nutritional Biochemistry, 1998 - Elsevier
Proprietary formulations of the amino acid L-histidine are under development as
pharmaceutical agents because of the molecule's antioxidant and anti-inflammatory …

[HTML][HTML] Histidine metabolism and function

ME Brosnan, JT Brosnan - The Journal of Nutrition, 2020 - Elsevier
Histidine is a dietary essential amino acid because it cannot be synthesized in humans. The
WHO/FAO requirement for adults for histidine is 10 mg· kg body weight-1· d-1. Histidine is …

[HTML][HTML] Benefits and adverse effects of histidine supplementation

AE Thalacker-Mercer, ME Gheller - The Journal of nutrition, 2020 - Elsevier
Histidine is a nutritionally essential amino acid with many recognized benefits to human
health, while circulating concentrations of histidine decline in pathologic conditions [eg …

Evidence that histidine is an essential amino acid in normal and chronically uremic man.

JELD KoPPLE, ME Swendseid - The Journal of clinical …, 1975 - Am Soc Clin Investig
The requirement for dietary histidine was investigated in four normal and three chronically
uremic men. Subjects lived in a metabolic unit where they were fed three isonitrogenous …

Histidine-induced injury to cultured liver cells, effects of histidine derivatives and of iron chelators

U Rauen, S Klempt, H De Groot - Cellular and molecular life sciences, 2007 - Springer
The amino acid histidine is an excellent buffer and is therefore included in several organ
preservation solutions used in transplantation medicine. However, when used at …

Histidase and histidinemia. Clinical and molecular considerations.

RG Taylor, HL Levy, RR McInnes - Molecular biology & medicine, 1991 - europepmc.org
Histidase (histidine ammonia-lyase, EC 4.3. 1.3) catalyzes the deamination of L-histidine to
trans-urocanic acid in the liver and skin of mammals. Histidase deficiency results in …

[HTML][HTML] Toxicity of methionine in humans

PJ Garlick - The Journal of nutrition, 2006 - Elsevier
The literature has been searched to identify evidence relating to the possible toxicity of the
amino acid methionine in human subjects. Nutritional and metabolic studies have employed …

The metabolic roles, pharmacology, and toxicology of lysine.

NW Flodin - Journal of the American College of Nutrition, 1997 - Taylor & Francis
L-lysine monohydrochloride (LMH) is widely available to the public as a nonprescription oral
supplement. Most of the pharmaceutical-grade product is used as a suppressant of recurrent …