COVID-19–related anosmia is associated with viral persistence and inflammation in human olfactory epithelium and brain infection in hamsters

GD De Melo, F Lazarini, S Levallois… - Science translational …, 2021 - science.org
Whereas recent investigations have revealed viral, inflammatory, and vascular factors
involved in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lung …

Mechanisms of SARS-CoV-2-associated anosmia

T Tsukahara, DH Brann, SR Datta - Physiological Reviews, 2023 - journals.physiology.org
Anosmia, the loss of the sense of smell, is one of the main neurological manifestations of
COVID-19. Although the SARS-CoV-2 virus targets the nasal olfactory epithelium, current …

Proinflammatory cytokines in the olfactory mucosa result in COVID-19 induced anosmia

A Torabi, E Mohammadbagheri… - ACS chemical …, 2020 - ACS Publications
Studies have found increased rates of dysosmia in patients with Novel Coronavirus disease
2019 (COVID-19). However, the mechanism that causes olfactory loss is unknown. The …

COVID-19 anosmia: high prevalence, plural neuropathogenic mechanisms, and scarce neurotropism of SARS-CoV-2?

F Liang, DY Wang - Viruses, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative pathogen
of coronavirus disease 2019 (COVID-19). It is known as a respiratory virus, but SARS-CoV-2 …

COVID-19-related anosmia: the olfactory pathway hypothesis and early intervention

A Gori, F Leone, L Loffredo, BL Cinicola… - Frontiers in …, 2020 - frontiersin.org
Anosmia is a well-described symptom of Corona Virus Disease 2019 (COVID-19). Several
respiratory viruses are able to cause post-viral olfactory dysfunction, suggesting a …

Recovery of anosmia in hamsters infected with SARS-CoV-2 is correlated with repair of the olfactory epithelium

RA Reyna, M Kishimoto-Urata, S Urata, T Makishima… - Scientific reports, 2022 - nature.com
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for a
pandemic affecting billions of people worldwide. Apart from the extreme global economic …

Regeneration profiles of olfactory epithelium after SARS-CoV-2 infection in golden Syrian hamsters

S Urata, J Maruyama, M Kishimoto-Urata… - ACS chemical …, 2021 - ACS Publications
Olfactory dysfunction is one of the most frequent and specific symptoms of coronavirus
disease 2019 (COVID-19). Information on the damage and repair of the neuroepithelium …

Anosmia in COVID-19: underlying mechanisms and assessment of an olfactory route to brain infection

R Butowt, CS von Bartheld - The Neuroscientist, 2021 - journals.sagepub.com
In recent months it has emerged that the novel coronavirus—responsible for the COVID-19
pandemic—causes reduction of smell and taste in a large fraction of patients. The …

Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia

DH Brann, T Tsukahara, C Weinreb, M Lipovsek… - Science …, 2020 - science.org
Altered olfactory function is a common symptom of COVID-19, but its etiology is unknown. A
key question is whether SARS-CoV-2 (CoV-2)–the causal agent in COVID-19–affects …

Anosmia: a missing link in the neuroimmunology of coronavirus disease 2019 (COVID-19)

N Yazdanpanah, A Saghazadeh… - Reviews in the …, 2020 - degruyter.com
Just before 2020 began, a novel coronavirus, severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2), brought for humans a potentially fatal disease known as …