[HTML][HTML] Mitophagy-mediated molecular subtypes depict the hallmarks of the tumour metabolism and guide precision chemotherapy in pancreatic adenocarcinoma

H Chen, J Zhang, X Sun, Y Wang… - Frontiers in Cell and …, 2022 - frontiersin.org
Background: Mitophagy is closely related to cancer initiation and progression. However,
heterogeneity with reference to mitophagy remains unexplored in pancreatic …

[HTML][HTML] Mitophagy-related gene signature for prediction prognosis, immune scenery, mutation, and chemotherapy response in pancreatic cancer

Z Zhuo, H Lin, J Liang, P Ma, J Li, L Huang… - Frontiers in Cell and …, 2022 - frontiersin.org
Mitophagy is a conserved cellular process that plays a vital role in maintaining cellular
homeostasis by selectively removing dysfunctional mitochondria. Notwithstanding that …

[HTML][HTML] Identification of HCC subtypes with different prognosis and metabolic patterns based on mitophagy

Y Wang, Z Wang, J Sun, Y Qian - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
Background Mitophagy is correlated with tumor initiation and development of malignancy.
However, HCC heterogeneity with reference to mitophagy has yet not been systematically …

[HTML][HTML] The prognostic value and clinical significance of mitophagy-related genes in hepatocellular carcinoma

W Xu, D Zhao, X Huang, M Zhang, M Yin, L Liu… - Frontiers in …, 2022 - frontiersin.org
Background: Mitophagy has been found to play a significant part in the cancer process in a
growing number of studies in recent years. However, there is still a lack of study on …

[HTML][HTML] Identifying mitophagy-related genes as prognostic biomarkers and therapeutic targets of gastric carcinoma by integrated analysis of single-cell and bulk-RNA …

Z Wang, C Chen, J Ai, J Shu, Y Ding, W Wang… - Computers in Biology …, 2023 - Elsevier
Gastric carcinoma (GC) is the fourth leading cause of cancer-related mortality worldwide.
Patients with advanced GC tend to have poor prognoses and shortened survival. Finding …

[HTML][HTML] Mitophagy in pancreatic cancer

Y Xie, J Liu, R Kang, D Tang - Frontiers in Oncology, 2021 - frontiersin.org
Pancreatic ductal adenocarcinoma (PDAC), one of the most aggressive solid malignancies,
is characterized by the presence of oncogenic KRAS mutations, poor response to current …

[HTML][HTML] A mitophagy-related gene signature for subtype identification and prognosis prediction of hepatocellular carcinoma

C Liu, Z Wu, L Wang, Q Yang, J Huang… - International Journal of …, 2022 - mdpi.com
Globally, hepatocellular carcinoma (HCC) is the sixth most common cancer. In this study, the
correlation between mitophagy and HCC prognosis was evaluated using data from The …

[HTML][HTML] A comprehensive analysis of the effects of key mitophagy genes on the progression and prognosis of lung adenocarcinoma

D Dai, L Liu, Y Guo, Y Shui, Q Wei - Cancers, 2022 - mdpi.com
Simple Summary Dysfunction and dysregulation of mitochondrial dynamics are implicated in
tumorigenesis. To avoid mitochondrial dysfunction, a quality control mechanism called …

[Retracted] Development and Validation of a Novel Mitophagy‐Related Gene Prognostic Signature for Hepatocellular Carcinoma Based on Immunoscore …

H Chen, J Wang, R Zeng, Y Luo, K Guo… - Journal of …, 2021 - Wiley Online Library
Emerging evidence suggested that mitophagy may play an important role in the progression
of hepatocellular carcinoma (HCC), whereas the association between mitophagy‐related …

MCT4 as a potential therapeutic target to augment gemcitabine chemosensitivity in resected pancreatic cancer

SH Lee, HK Hwang, WJ Lee, CM Kang - Cellular Oncology, 2021 - Springer
Background Pancreatic cancer is a devastating disease with a high relapse rate, even in
case of resectable pancreatic cancer. Here, we aimed to identify the prognostic significance …