Respiratory failure is the leading cause of COVID-19 death and disproportionately impacts
adults more than children. Here, we present a large-scale snATAC-seq dataset (90,980 …

Respiratory failure associated with COVID-19 has placed focus on the lungs. Here, we
present single-nucleus accessible chromatin profiles of 90,980 nuclei and matched single …

COVID-19 (Coronavirus Disease 2019) has been an ongoing pandemic, resulting in an
increase in people being infected globally. Understanding the potential risk of infection for …

Age is a major risk factor for severe coronavirus disease-2019 (COVID-19). Here, we
interrogate the transcriptional features and cellular landscape of the aging human lung. By …

Background: Infection by coronavirus SARS-CoV2 is a severe and often deadly disease that
has implications for the respiratory system and multiple organs across the human body …

The COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2, creates an urgent
need for identifying molecular mechanisms that mediate viral entry, propagation, and tissue …

The molecular mechanisms underlying the clinical manifestations of coronavirus disease
2019 (COVID-19), and what distinguishes them from common seasonal influenza virus and …

The SARS-CoV-2 pandemic has caused over 1 million deaths globally, mostly due to acute
lung injury and acute respiratory distress syndrome, or direct complications resulting in …

Recently, emerging evidence has indicated that COVID-19 represents a major threat to older
populations, but the underlying mechanisms remain unclear. The pathogen causing COVID …

Individuals infected with the SARS-CoV-2 virus present with a wide variety of symptoms
ranging from asymptomatic to severe and even lethal outcomes. Past research has revealed …