The association between adverse childhood experiences and epigenetic age acceleration in the Canadian longitudinal study on aging (CLSA)
Research examining the association between exposure to a wide range of adverse
childhood experiences (ACEs) and accelerated biological aging in older adults is limited …
childhood experiences (ACEs) and accelerated biological aging in older adults is limited …
Adversity exposure during sensitive periods predicts accelerated epigenetic aging in children
Objectives Exposure to adversity has been linked to accelerated biological aging, which in
turn has been shown to predict numerous physical and mental health problems. In recent …
turn has been shown to predict numerous physical and mental health problems. In recent …
Early adversities accelerate epigenetic aging into adulthood: a 10‐year, within‐subject analysis
WE Copeland, L Shanahan… - Journal of Child …, 2022 - Wiley Online Library
Background Longitudinal studies are needed to clarify whether early adversities are
associated with advanced methylation age or if they actually accelerate methylation aging …
associated with advanced methylation age or if they actually accelerate methylation aging …
Association of adverse childhood experiences with accelerated epigenetic aging in midlife
Importance Adverse childhood experiences (ACEs) are associated with the risk of poorer
health, and identifying molecular mechanisms may lay the foundation for health promotion in …
health, and identifying molecular mechanisms may lay the foundation for health promotion in …
Early life adversity and age acceleration at mid-life and older ages indexed using the next-generation GrimAge and Pace of Aging epigenetic clocks
Objective This retrospective cross-sectional study was designed to explore whether the
experience of childhood adversity was associated with epigenetic age acceleration in mid …
experience of childhood adversity was associated with epigenetic age acceleration in mid …
The impact of psychosocial stress from life trauma and racial discrimination on epigenetic aging—a systematic review
Purpose The purpose of this review was to explore the effects of psychosocial stress from life
trauma and racial discrimination on epigenetic aging. Design A systematic review of the last …
trauma and racial discrimination on epigenetic aging. Design A systematic review of the last …
[HTML][HTML] Maternal adverse childhood experiences before pregnancy are associated with epigenetic aging changes in their children
JC Nwanaji-Enwerem, L Van Der Laan, K Kogut… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Emerging research suggests associations of physical and psychosocial stressors with
epigenetic aging. Although this work has included early-life exposures, data on maternal …
epigenetic aging. Although this work has included early-life exposures, data on maternal …
[HTML][HTML] Associations between exposure to adverse childhood experiences and biological aging: evidence from the Canadian Longitudinal Study on Aging
People exposed to adverse childhood experiences (ACEs) suffer from an increased risk of
chronic disease and shorter lifespan. These individuals also tend to exhibit accelerated …
chronic disease and shorter lifespan. These individuals also tend to exhibit accelerated …
Use of correct and incorrect methods of accounting for age in studies of epigenetic accelerated aging: implications and recommendations for best practices
Motivated by our conduct of a literature review on social exposures and accelerated aging
as measured by a growing number of epigenetic “clocks”(which estimate age via DNA …
as measured by a growing number of epigenetic “clocks”(which estimate age via DNA …
Early life adversity, pubertal timing, and epigenetic age acceleration in adulthood
Background Given associations linking early life adversity, pubertal timing, and biological
aging, we examined the direct and indirect effects of early life trauma on adult biological …
aging, we examined the direct and indirect effects of early life trauma on adult biological …