The development of mouse models for coronavirus disease 2019 (COVID-19) has enabled testing of vaccines and therapeutics and defining aspects of severe acute respiratory …
W Dong, H Mead, L Tian, JG Park, JI Garcia… - Journal of …, 2022 - Am Soc Microbiol
ABSTRACT A comprehensive analysis and characterization of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection model that mimics non-severe and severe …
JA Harker, C Johansson - American Journal of Respiratory Cell and …, 2021 - atsjournals.org
The global severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic continues to progress quickly, with over 36 million people infected and over 1 million deaths …
ABSTRACT Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) emerged in late 2019 and has spread worldwide resulting in the Coronavirus Disease 2019 (COVID-19) …
IW Song, M Washington, C Leynes, J Hsu… - Mammalian …, 2024 - Springer
Abstract The Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) remains a public health concern and a subject of active research effort. Development of pre-clinical …
R Gawish, P Starkl, L Pimenov, A Hladik, K Lakovits… - Elife, 2022 - elifesciences.org
Despite tremendous progress in the understanding of COVID-19, mechanistic insight into immunological, disease-driving factors remains limited. We generated maVie16, a mouse …
SH Sun, Q Chen, HJ Gu, G Yang, YX Wang… - Cell host & …, 2020 - cell.com
Since December 2019, a novel coronavirus SARS-CoV-2 has emerged and rapidly spread throughout the world, resulting in a global public health emergency. The lack of vaccine and …
H Chu, JFW Chan - EBioMedicine, 2021 - thelancet.com
Since its discovery in December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused over 146 million cases of Coronavirus Disease 2019 (COVID …
L Hassler, J Wysocki, I Gelarden, A Tomatsidou, H Gula… - BioRxiv, 2021 - biorxiv.org
Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) uses full-length angiotensin converting enzyme 2 (ACE2), which is membrane bound, as its initial cell …