An emerging body of data suggests that lipid metabolism has an important role to play in the
aging process. Indeed, a plethora of dietary, pharmacological, genetic, and surgical lipid …

Lipids play crucial roles in regulating aging and longevity. In the past few decades, a series
of genetic pathways have been discovered to regulate lifespan in model organisms …

The lifespan of an organism is strongly influenced by environmental factors (including diet)
and by internal factors (notably reproductive status). Lipid metabolism is critical for …

During aging, body adiposity increases with changes in the metabolism of lipids and their
metabolite levels. Considering lipid metabolism, excess adiposity with increased lipotoxicity …

Lipids are key macromolecules that perform a multitude of biological functions ranging from
maintaining structural integrity of membranes, energy storage, to signaling molecules …

Phospholipids are major membrane lipids that consist of lipid bilayers. This basic cellular
structure acts as a barrier to protect the cell against various environmental insults and more …

Middle‐aged offspring of nonagenarians, as compared to their spouses (controls), show a
favorable lipid metabolism marked by larger LDL particle size in men and lower total …

Many lifespan-modulating genes are involved in either generation of oxidative substrates
and end-products, or their detoxification and removal. Among such metabolites, only …

Diseases including cancer, type 2 diabetes, cardiovascular and immune dysfunction and
neurodegeneration become more prevalent as we age, and combined with the increase in …

The dietary intake of ω‐3 polyunsaturated fatty acids has been linked to a reduction in the
incidence of aging‐associated disease including cardiovascular disease and stroke …