W Dan, J Dai - European journal of medicinal chemistry, 2020 - Elsevier
Chalcones, containing an α, β-unsaturated ketone fragment, are an important pharmacologically active agents because of their diverse mechanisms. This review provides …
Chalcones have been well examined in the extant literature and demonstrated antibacterial, antifungal, anti-inflammatory, and anticancer properties. A detailed evaluation of the …
D Gupta, D Jain, P Trivedi - Int. J. Chem. Sci, 2010 - hakon-art.com
Chalcones are important precursors of flavonoids and isoflavonoids. Naturally occuring and synthetic chalcones show various biological effects, eg anti-inflammatory, antitumour …
Chalcones are promising synthons and bioactive scaffolds of great medicinal interest due to their numerous pharmacological and biological activities. They are well recognized to …
M Ritter, R Mastelari Martins, D Dias… - Letters in Organic …, 2014 - ingentaconnect.com
The increasing resistance of bacteria and fungi to antimicrobial drugs has been a matter of concern in public health in the last decades. The continuing need for novel therapeutic …
M Xu, P Wu, F Shen, J Ji, KP Rakesh - Bioorganic Chemistry, 2019 - Elsevier
The increase in antibiotic resistance due to various factors has encouraged the look for novel compounds which are active against multidrug-resistant pathogens. In this framework …
ATL Dos Santos, JB de Araújo-Neto, MMC da Silva… - Microbial …, 2023 - Elsevier
The increased resistance of microorganisms to antimicrobial drugs makes it necessary to search for new active compounds, such as chalcones. Their simple chemical structure …
G Rajendran, D Bhanu, B Aruchamy, P Ramani… - Pharmaceuticals, 2022 - mdpi.com
Chalcones are a class of privileged scaffolds with high medicinal significance due to the presence of an α, β-unsaturated ketone functionality. Numerous functional modifications of …