[HTML][HTML] Effects of bone substitute architecture and surface properties on cell response, angiogenesis, and structure of new bone

FSL Bobbert, AA Zadpoor - Journal of Materials Chemistry B, 2017 - pubs.rsc.org
The success of bone substitutes used to repair bone defects such as critical sized defects
depends on the architecture of the porous biomaterial. The architectural parameters and …

Role of pore size and morphology in musculo-skeletal tissue regeneration

RA Perez, G Mestres - Materials Science and Engineering: C, 2016 - Elsevier
Biomaterials in the form of scaffolds hold great promise in the regeneration of diseased
tissues. The scaffolds stimulate cellular adhesion, proliferation and differentiation. While the …

Effect of micro-and macroporosity of bone substitutes on their mechanical properties and cellular response

A Bignon, J Chouteau, J Chevalier, G Fantozzi… - Journal of Materials …, 2003 - Springer
The control of porosity morphology and physico-chemical characteristics of calcium
phosphate bone substitutes is a key-point to guaranty healing success. In this work, micro …

[HTML][HTML] Bone biomaterials and interactions with stem cells

C Gao, S Peng, P Feng, C Shuai - Bone research, 2017 - nature.com
Bone biomaterials play a vital role in bone repair by providing the necessary substrate for
cell adhesion, proliferation, and differentiation and by modulating cell activity and function. In …

[HTML][HTML] Porous scaffolds for bone regeneration

N Abbasi, S Hamlet, RM Love, NT Nguyen - Journal of science: advanced …, 2020 - Elsevier
Globally, bone fractures due to osteoporosis occur every 20 s in people aged over 50 years.
The significant healthcare costs required to manage this problem are further exacerbated by …

State of the art and future directions of scaffold‐based bone engineering from a biomaterials perspective

DW Hutmacher, JT Schantz, CXF Lam… - Journal of tissue …, 2007 - Wiley Online Library
Scaffold‐based bone tissue engineering aims to repair/regenerate bone defects. Such a
treatment concept involves seeding autologous osteogenic cells throughout a …

Polymeric scaffolds for bone tissue engineering

X Liu, PX Ma - Annals of biomedical engineering, 2004 - Springer
Bone tissue engineering is a rapidly developing area. Engineering bone typically uses an
artificial extracellular matrix (scaffold), osteoblasts or cells that can become osteoblasts, and …

How does scaffold porosity conduct bone tissue regeneration?

H Mohammadi, M Sepantafar… - Advanced …, 2021 - Wiley Online Library
Pores play a crucial role in bone regeneration as they allow the exchange of nutrition and
oxygen, expulsion of waste products, and bone tissue and vascular ingrowth through the …

Hydrophobicity as a design criterion for polymer scaffolds in bone tissue engineering

EJP Jansen, REJ Sladek, H Bahar, A Yaffe, MJ Gijbels… - Biomaterials, 2005 - Elsevier
Porous polymeric scaffolds play a key role in most tissue-engineering strategies. A series of
non-degrading porous scaffolds was prepared, based on bulk-copolymerisation of 1-vinyl-2 …

High-strength porous biomaterials for bone replacement: A strategy to assess the interplay between cell morphology, mechanical properties, bone ingrowth and …

S Arabnejad, RB Johnston, JA Pura, B Singh, M Tanzer… - Acta biomaterialia, 2016 - Elsevier
High-strength fully porous biomaterials built with additive manufacturing provide an exciting
opportunity for load-bearing orthopedic applications. While factors controlling their …