Recent studies have mapped key genetic changes in colorectal cancer (CRC) that impact
important pathways contributing to the multistep models for CRC initiation and development …

Colorectal cancer (CRC) is one of the most common causes of death, despite decades of
research. Initially considered as a disease due to genetic mutations, it is now viewed as a …

Colorectal cancer (CRC) is a complex disease characterized by genetic and epigenetic
alterations, playing a crucial role in its development and progression. This review aims to …

Colorectal cancer (CRC) is a heterogeneous disease, arising from many possible etiological
pathways. This heterogeneity can have important implications for CRC prognosis and …

Originally, colorectal cancer (CRC) tumorigenesis was understood as a multistep process
that involved accumulation of tumor suppressor genes and oncogenes mutations, such as …

Colorectal cancer (CRC) has predominantly been considered a genetic disease,
characterized by sequential accumulation of genetic alterations. Growing evidence indicates …

Colorectal cancer (CRC) arise from multi-step carcinogenesis due to genetic mutations and
epigenetic modifications of human genome. Genetic mutations and epigenetic modifications …

Cancer is a heterogeneous disease caused, in part, by genetic and epigenetic alterations.
These changes have been explored in studies of the pathogenesis of colorectal cancer …

Colorectal cancer (CRC) is a complex disease that develops as a consequence of both
genetic and environmental risk factors. A small proportion (3–5%) of cases arise from …

Purpose The molecular pathogenesis of solid tumour was first assessed in colorectal cancer
(CRC). To date,≤ 100 genes with somatic alterations have been found to inter-connectively …