Total extracellular small RNA profiles from plasma, saliva, and urine of healthy subjects

A Yeri, A Courtright, R Reiman, E Carlson, T Beecroft… - Scientific reports, 2017 - nature.com
Interest in circulating RNAs for monitoring and diagnosing human health has grown
significantly. There are few datasets describing baseline expression levels for total cell-free …

Human plasma and serum extracellular small RNA reference profiles and their clinical utility

KEA Max, K Bertram, KM Akat… - Proceedings of the …, 2018 - National Acad Sciences
Circulating extracellular RNAs (exRNAs) have the potential to serve as biomarkers for a
wide range of medical conditions. However, limitations in existing exRNA isolation methods …

High throughput sequencing of extracellular RNA from human plasma

KM Danielson, R Rubio, F Abderazzaq, S Das… - PLoS …, 2017 - journals.plos.org
The presence and relative stability of extracellular RNAs (exRNAs) in biofluids has led to an
emerging recognition of their promise as 'liquid biopsies' for diseases. Most prior studies on …

Discordant expression of circulating microRNA from cellular and extracellular sources

R Shah, K Tanriverdi, D Levy, M Larson, M Gerstein… - PloS one, 2016 - journals.plos.org
MicroRNA (miRNA) expression has rapidly grown into one of the largest fields for disease
characterization and development of clinical biomarkers. Consensus is lacking in regards to …

The complex exogenous RNA spectra in human plasma: an interface with human gut biota?

K Wang, H Li, Y Yuan, A Etheridge, Y Zhou, D Huang… - PloS one, 2012 - journals.plos.org
Human plasma has long been a rich source for biomarker discovery. It has recently become
clear that plasma RNA molecules, such as microRNA, in addition to proteins are common …

[HTML][HTML] Large differences in small RNA composition between human biofluids

PM Godoy, NR Bhakta, AJ Barczak, H Cakmak… - Cell reports, 2018 - cell.com
Extracellular microRNAs (miRNAs) and other small RNAs are implicated in cellular
communication and may be useful as disease biomarkers. We systematically compared …

Standardizing analysis of circulating microRNA: clinical and biological relevance

NH Farina, ME Wood, SD Perrapato… - Journal of cellular …, 2014 - Wiley Online Library
Circulating microRNAs (c‐miRNAs) provide a new dimension as clinical biomarkers for
disease diagnosis, progression, and response to treatment. However, the discovery of …

Extracellular RNA in a single droplet of human serum reflects physiologic and disease states

Z Zhou, Q Wu, Z Yan, H Zheng… - Proceedings of the …, 2019 - National Acad Sciences
Extracellular RNAs (exRNAs) are present in human serum. It remains unclear to what extent
these circulating exRNAs may reflect human physiologic and disease states. Here, we …

Plasma or serum? A qualitative study on rodents and humans using high-throughput microRNA sequencing for circulating biomarkers

T Dufourd, N Robil, D Mallet, C Carcenac… - Biology Methods and …, 2019 - academic.oup.com
Abstract microRNAs are small non-coding RNAs gaining interest for their potential roles as
reliable biomarkers for the diagnosis and therapeutics of numerous pathologies, ranging …

The origin, function and diagnostic potential of extracellular microRNA in human body fluids

A Turchinovich, WC Cho - Frontiers in genetics, 2014 - frontiersin.org
Over the past several years extracellular microRNAs (miRNAs) have been found in all
mammalian body fluids such as blood plasma, saliva, urine, milk, seminal plasma, tears, and …