Papillary Thyroid Cancer Remodels the Genomic Fabrics of DNA Replication, Repair and Transcription

DA Iacobas, S Iacobas - 2024 - preprints.org
The genetic causes of the differentiated, highly treatable and mostly non-fatal papillary
thyroid cancer (PTC) are not yet fully known. The widely accepted PTC etiology blames …

[HTML][HTML] Papillary Thyroid Cancer Remodels the Genetic Information Processing Pathways

DA Iacobas, S Iacobas - Genes, 2024 - mdpi.com
The genetic causes of the differentiated, highly treatable, and mostly non-fatal papillary
thyroid cancer (PTC) are not yet fully understood. The mostly accepted PTC etiology blames …

[HTML][HTML] Biomarkers, master regulators and genomic fabric remodeling in a case of papillary thyroid carcinoma

DA Iacobas - Genes, 2020 - mdpi.com
Publicly available (own) transcriptomic data have been analyzed to quantify the alteration in
functional pathways in thyroid cancer, establish the gene hierarchy, identify potential gene …

[HTML][HTML] Transcriptomic signature associated with carcinogenesis and aggressiveness of papillary thyroid carcinoma

H Teng, F Mao, J Liang, M Xue, W Wei, X Li… - Theranostics, 2018 - ncbi.nlm.nih.gov
Papillary thyroid carcinoma (PTC) is the fastest-growing disease caused by numerous
molecular alterations in addition to previously reported DNA mutations. There is a …

[HTML][HTML] Identification of candidate genes associated with papillary thyroid carcinoma pathogenesis and progression by weighted gene co-expression network …

X Chen, R Wang, T Xu, Y Zhang, H Li… - Translational Cancer …, 2021 - ncbi.nlm.nih.gov
Background The genes and genetic mechanisms underlying the occurrence and
progression of papillary thyroid carcinoma (PTC) are still unknown. This study aimed to find …

The specific regulatory networks between different variants in papillary thyroid carcinoma: A transcriptomics study

LJ Xie, S Yang, R He, T Wang, Z Yang, S Song, J Feng… - 2023 - researchsquare.com
Objective: To analyze the molecular pathogenesis or characteristics based on
transcriptomics techniques to diagnose and treat papillary thyroid carcinoma (PTC) caused …

Identification and validation of core genes involved in the development of papillary thyroid carcinoma via bioinformatics analysis

X Li, J He, M Zhou, Y Cao, Y Jin… - International Journal of …, 2019 - Wiley Online Library
Background. Papillary thyroid carcinoma (PTC) is a common endocrine malignant
neoplasm, and its incidence increases continuously worldwide in the recent years. However …

[HTML][HTML] Transcriptome analysis discloses dysregulated genes in normal appearing tumor-adjacent thyroid tissues from patients with papillary thyroid carcinoma

H He, S Liyanarachchi, W Li, DF Comiskey Jr, P Yan… - Scientific Reports, 2021 - nature.com
Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. The molecular
characteristics of histologically normal appearing tissue adjacent to the tumor (NAT) from …

[HTML][HTML] Systems biology approaches to investigate genetic and epigenetic molecular progression mechanisms for identifying gene expression signatures in papillary …

SJ Yeh, CY Lin, CW Li, BS Chen - International journal of molecular …, 2019 - mdpi.com
Thyroid cancer is the most common endocrine cancer. Particularly, papillary thyroid cancer
(PTC) accounts for the highest proportion of thyroid cancer. Up to now, there are few …

Integrative Analysis of Potential Biomarkers Involved in the Progression of Papillary Thyroid Cancer

R Bansal, U Saxena - Applied biochemistry and biotechnology, 2023 - Springer
This study aims to explore key prognostic and diagnostic biomarkers involved in the
pathogenesis of papillary thyroid cancer (PTC) which is one of the most common endocrine …