Vaccines represent one of the greatest triumphs of modern medicine. Despite the common
origins of vaccinology and immunology more than 200 years ago, the two disciplines have …

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Although the field of immunology developed in part from the early vaccine studies of Edward
Jenner, Louis Pasteur and others, vaccine development had largely become the province of …

Some recently introduced vaccines that have excellent efficacy records have been
developed without a clear understanding of their mechanism of protection. In fact, successful …

For more than a century, immunologists and vaccinologists have existed in parallel
universes. Immunologists have for long reveled in using 'model antigens', such as chicken …

Abstract Systems vaccinology has defined molecular signatures and mechanisms of
immunity to vaccination. However, comparative analysis of immunity to different vaccines is …

The immune system is a network of specialized cell types and tissues that communicates via
cytokines and direct contact, to orchestrate specific types of defensive responses. Until …

Vaccines represent a potent tool to prevent or contain infectious diseases with high
morbidity or mortality. However, despite their widespread use, we still have a limited …

Introduction: Three major advances have led to increase in length and quality of human life:
increased food production, improved sanitation and induction of specific adaptive immune …

Recent epidemiological studies have shown that, in addition to disease-specific effects,
vaccines against infectious diseases have nonspecific effects on the ability of the immune …