The development of the vertebrate eyes is a complex process starting from anterior-posterior
and dorso-ventral patterning of the anterior neural tube, resulting in the formation of the eye …

Three embryonic tissue sources—the neural ectoderm, the surface ectoderm, and the
periocular mesenchyme—contribute to the formation of the mammalian eye. For this reason …

Organogenesis of the eye is a multistep process that starts with the formation of optic
vesicles followed by invagination of the distal domain of the vesicles and the overlying lens …

The vertebrate eye is composed of both surface ectodermal and neuroectodermal
derivatives that evaginate laterally from an epithelial anlage of the forming diencephalon …

Retinal development and maturation are orchestrated by a series of interacting signalling
networks that drive the morphogenetic transformation of the anterior developing brain …

Homeobox genes are an evolutionarily conserved class of transcription factors that are
critical for development of many organ systems, including the brain and eye. During …

The plasticity of pluripotent stem cells provides new possibilities for studying development,
degeneration, and regeneration. Protocols for the differentiation of retinal organoids from …

The specification of embryonic cells to produce the retina begins at early embryonic stages
as a multi‐step process that gradually restricts fate potentials. First, a subset of embryonic …

Eye development is a complex and highly regulated process that consists of several
overlapping stages:(i) specification then splitting of the eye field from the developing …

A major goal in the stem cell field is to generate tissues that can be utilized as a universal
tool for in vitro models of development and disease, drug development, or as a resource for …