Small-magnitude effect sizes in epigenetic end points are important in children's environmental health studies: the children's environmental health and disease …

CV Breton, CJ Marsit, E Faustman… - Environmental …, 2017 - ehp.niehs.nih.gov
Background: Characterization of the epigenome is a primary interest for children's
environmental health researchers studying the environmental influences on human …

Epigenetic epidemiology: promises for public health research

KM Bakulski, MD Fallin - Environmental and molecular …, 2014 - Wiley Online Library
Epigenetic changes underlie developmental and age related biology. Promising
epidemiologic research implicates epigenetics in disease risk and progression, and …

Epigenomics in environmental health

BC Christensen, CJ Marsit - Frontiers in genetics, 2011 - frontiersin.org
This review considers the emerging relationships between environmental factors and
epigenetic alterations and the application of genome-wide assessments to better define …

Environmental exposures and gene regulation in disease etiology

TM Edwards, JP Myers - Environmental health perspectives, 2007 - ehp.niehs.nih.gov
Objective Health or disease is shaped for all individuals by interactions between their genes
and environment. Exactly how the environment changes gene expression and how this can …

DNA methylation, early life environment, and health outcomes

C Mitchell, LM Schneper, DA Notterman - Pediatric research, 2016 - nature.com
Epigenetics, and especially DNA methylation, have recently become provocative biological
explanations for early-life environmental effects on later health. Despite the large increase in …

Environmental epigenetics and its implication on disease risk and health outcomes

SM Ho, A Johnson, P Tarapore, V Janakiram… - ILAR …, 2012 - academic.oup.com
This review focuses on how environmental factors through epigenetics modify disease risk
and health outcomes. Major epigenetic events, such as histone modifications, DNA …

Environmental chemical exposures and human epigenetics

L Hou, X Zhang, D Wang… - International journal of …, 2012 - academic.oup.com
Every year more than 13 million deaths worldwide are due to environmental pollutants, and
approximately 24% of diseases are caused by environmental exposures that might be …

Environmental chemicals and DNA methylation in adults: a systematic review of the epidemiologic evidence

A Ruiz-Hernandez, CC Kuo, P Rentero-Garrido… - Clinical …, 2015 - Springer
Current evidence supports the notion that environmental exposures are associated with
DNA-methylation and expression changes that can impact human health. Our objective was …

The promises and challenges of toxico-epigenomics: environmental chemicals and their impacts on the epigenome

FFL Chung, Z Herceg - Environmental Health Perspectives, 2020 - ehp.niehs.nih.gov
Background: It has been estimated that a substantial portion of chronic and
noncommunicable diseases can be caused or exacerbated by exposure to environmental …

Epigenetic signatures as biomarkers of exposure

C Ladd-Acosta - Current environmental health reports, 2015 - Springer
To advance our knowledge of the influence of environmental exposures on human health
and disease, robust studies are needed. However, for many exposures, robust studies are …