The history of Alzheimer's disease (AD) started in 1907, but we needed to wait until the end
of the century to identify the components of pathological hallmarks and genetic subtypes and …

Alzheimer's disease (AD) is a fast growing world-wide epidemic. AD is a genetically
complex, slowly progressive, and irreversible neurodegenerative disease of the brain …

The inability to effectively halt or cure Alzheimer's disease (AD), exacerbated by the recent
failures of high-profile clinical trials, emphasizes the urgent need to understand the complex …

Alzheimer's disease, the commonest cause of dementia, is a growing global health concern
with huge implications for individuals and society. In this review, current understanding of …

Alzheimer disease (AD) is the most common type of dementia, and is currently incurable;
existing treatments for AD produce only a modest amelioration of symptoms. Research into …

Alzheimer disease (AD) is biologically defined by the presence of β-amyloid-containing
plaques and tau-containing neurofibrillary tangles. AD is a genetic and sporadic …

Alzheimer's disease (AD) is the most common form of dementia, which affects more than 35
million people worldwide with increasing tendency. Satisfying therapies and prevention are …

The search for the genetic factors contributing to Alzheimer disease (AD) has evolved
tremendously throughout the years. It started from the discovery of fully penetrant mutations …

Since the description by Alois Alzheimer, more than 50 years have passed during which
senile dementia and pre-senile dementia have been considered Alzheimer disease (AD) on …

The global prevalence of dementia is as high as 24 million, and has been predicted to
quadruple by the year 2050. In the US alone, Alzheimer disease (AD)–the most frequent …