A mammalian methylation array for profiling methylation levels at conserved sequences
Infinium methylation arrays are not available for the vast majority of non-human mammals.
Moreover, even if species-specific arrays were available, probe differences between them …
Moreover, even if species-specific arrays were available, probe differences between them …
Meta-analysis of human methylomes reveals stably methylated sequences surrounding CpG islands associated with high gene expression
Background DNA methylation is thought to play an important role in the regulation of
mammalian gene expression, partly based on the observation that a lack of CpG island …
mammalian gene expression, partly based on the observation that a lack of CpG island …
Additional annotation enhances potential for biologically-relevant analysis of the Illumina Infinium HumanMethylation450 BeadChip array
Background Measurement of genome-wide DNA methylation (DNAm) has become an
important avenue for investigating potential physiologically-relevant epigenetic changes …
important avenue for investigating potential physiologically-relevant epigenetic changes …
Genome-scale DNA methylation analysis
SD Fouse, RP Nagarajan, JF Costello - Epigenomics, 2010 - Future Medicine
The haploid human genome contains approximately 29 million CpGs that exist in a
methylated, hydroxymethylated or unmethylated state, collectively referred to as the DNA …
methylated, hydroxymethylated or unmethylated state, collectively referred to as the DNA …
Complete pipeline for Infinium® Human Methylation 450K BeadChip data processing using subset quantile normalization for accurate DNA methylation estimation
N Touleimat, J Tost - Epigenomics, 2012 - Future Medicine
Background: Huge progress has been made in the development of array-or sequencing-
based technologies for DNA methylation analysis. The Illumina Infinium® Human …
based technologies for DNA methylation analysis. The Illumina Infinium® Human …
Genome-scale DNA methylation maps of pluripotent and differentiated cells
DNA methylation is essential for normal development,, and has been implicated in many
pathologies including cancer,. Our knowledge about the genome-wide distribution of DNA …
pathologies including cancer,. Our knowledge about the genome-wide distribution of DNA …
Genome-wide DNA methylation profiling using Infinium® assay
M Bibikova, J Le, B Barnes, S Saedinia-Melnyk… - …, 2009 - Taylor & Francis
Aims: Bisulfite sequence analysis of individual CpG sites within genomic DNA is a powerful
approach for methylation analysis in the genome. The major limitation of bisulfite-based …
approach for methylation analysis in the genome. The major limitation of bisulfite-based …
Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells
Studies of epigenetic modifications would benefit from improved methods for high-
throughput methylation profiling. We introduce two complementary approaches that use next …
throughput methylation profiling. We introduce two complementary approaches that use next …
A DNA methylation atlas of normal human cell types
DNA methylation is a fundamental epigenetic mark that governs gene expression and
chromatin organization, thus providing a window into cellular identity and developmental …
chromatin organization, thus providing a window into cellular identity and developmental …
[HTML][HTML] Identification of polymorphic and off-target probe binding sites on the Illumina Infinium MethylationEPIC BeadChip
Genome-wide analysis of DNA methylation has now become a relatively inexpensive
technique thanks to array-based methylation profiling technologies. The recently developed …
technique thanks to array-based methylation profiling technologies. The recently developed …